Motivation: Bioinformatics is faced with a variety of problems that require human involvement.
Tasks like genome annotation, image analysis, knowledge-base population and protein …

The use of crowdsourcing to solve important but complex problems in biomedical and clinical
sciences is growing and encompasses a wide variety of approaches. The crowd is diverse …

The tissue-specific pattern of mRNA expression can indicate important clues about gene
function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene …

High-throughput gene expression profiling has become an important tool for investigating
transcriptional activity in a variety of biological samples. To date, the vast majority of these …

In mammals, circadian control of physiology and behavior is driven by a master pacemaker
located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene …

Detection, treatment, and prediction of outcome for men with prostate cancer increasingly
depend on a molecular understanding of tumor development and behavior. We characterized …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
has triggered an ongoing global pandemic of the severe pneumonia-like disease …

Classification of human tumors according to their primary anatomical site of origin is
fundamental for the optimal treatment of patients with cancer. Here we describe the use of large-…

We have examined the progression of hepatitis C virus (HCV) infections by gene expression
analysis of liver biopsies in acutely infected chimpanzees that developed persistent infection…

Online gene annotation resources are indispensable for analysis of genomics data. However,
the landscape of these online resources is highly fragmented, and scientists often visit …