User profiles for Andrew J Shoffstall
Andrew J ShoffstallAssistant Professor, Case Western Reserve University Verified email at case.edu Cited by 1466 |
[HTML][HTML] Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and-spheres in mice
…, LN Randolph, A VanMeter, S Hern, AJ Shoffstall… - Virology, 2014 - Elsevier
Understanding the pharmacokinetics, blood compatibility, biodistribution and clearance
properties of nanoparticles is of great importance to their translation to clinical application. In this …
properties of nanoparticles is of great importance to their translation to clinical application. In this …
Cyclodextrin-based device coatings for affinity-based release of antibiotics
TR Thatiparti, AJ Shoffstall, HA Von Recum - Biomaterials, 2010 - Elsevier
Cyclodextrin-based hydrogels were synthesized to create robust networks with tunable
mechanical properties capable of serving as device coatings. The CD networks were able to …
mechanical properties capable of serving as device coatings. The CD networks were able to …
Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation
Objective. Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly
few studies characterizing the anatomy of the vagus nerve in large animal models as it …
few studies characterizing the anatomy of the vagus nerve in large animal models as it …
[HTML][HTML] A mosquito inspired strategy to implant microprobes into the brain
AJ Shoffstall, S Srinivasan, M Willis, AM Stiller… - Scientific Reports, 2018 - nature.com
Mosquitos are among the deadliest insects on the planet due to their ability to transmit
diseases like malaria through their bite. In order to bite, a mosquito must insert a set of micro-sized …
diseases like malaria through their bite. In order to bite, a mosquito must insert a set of micro-sized …
[HTML][HTML] Microelectrode implantation in motor cortex causes fine motor deficit: Implications on potential considerations to Brain Computer Interfacing and Human …
M Goss-Varley, KR Dona, JA McMahon, AJ Shoffstall… - Scientific reports, 2017 - nature.com
Intracortical microelectrodes have shown great success in enabling locked-in patients to
interact with computers, robotic limbs, and their own electrically driven limbs. The recent …
interact with computers, robotic limbs, and their own electrically driven limbs. The recent …
Spatially selective stimulation of the pig vagus nerve to modulate target effect versus side effect
Electrical stimulation of the cervical vagus nerve using implanted electrodes (VNS) is FDA-approved
for the treatment of drug-resistant epilepsy, treatment-resistant depression, and …
for the treatment of drug-resistant epilepsy, treatment-resistant depression, and …
[HTML][HTML] Sources of off-target effects of vagus nerve stimulation using the helical clinical lead in domestic pigs
Objective Clinical data suggest that efficacious vagus nerve stimulation (VNS) is limited by
side effects such as cough and dyspnea that have stimulation thresholds lower than those for …
side effects such as cough and dyspnea that have stimulation thresholds lower than those for …
Potential for thermal damage to the blood–brain barrier during craniotomy: implications for intracortical recording microelectrodes
AJ Shoffstall, JE Paiz, DM Miller, GM Rial… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Our objective was to determine how readily disruption of the blood–brain barrier (BBB)
occurred as a result of bone drilling during a craniotomy to implant microelectrodes in …
occurred as a result of bone drilling during a craniotomy to implant microelectrodes in …
Intravenous hemostatic nanoparticles increase survival following blunt trauma injury
AJ Shoffstall, KT Atkins, RE Groynom… - …, 2012 - ACS Publications
Trauma is the leading cause of death for people ages 1–44, with blood loss comprising 60–70%
of mortality in the absence of lethal CNS or cardiac injury. Immediate intervention is …
of mortality in the absence of lethal CNS or cardiac injury. Immediate intervention is …
An injectable neural stimulation electrode made from an in‐body curing polymer/metal composite
Implanted neural stimulation and recording devices hold vast potential to treat a variety of
neurological conditions, but the invasiveness, complexity, and cost of the implantation …
neurological conditions, but the invasiveness, complexity, and cost of the implantation …