Sequencing the RNA in a biological sample can unlock a wealth of information, including
the identity of bacteria and viruses, the nuances of alternative splicing or the transcriptional …

The sequencing of individual DNA strands with nanopores is under investigation as a rapid,
low-cost platform in which bases are identified in order as the DNA strand is transported …

Recently, we demonstrated that submicrolitre aqueous droplets submerged in an apolar
liquid containing lipid can be tightly connected by means of lipid bilayers 1 , 2 , 3 , 4 , 5 to form …

Aqueous droplets in oil that are coated with lipid monolayers and joined through interface
bilayers 1 , 2 are useful for biophysical measurements on membrane proteins 2 , 3 , 4 , 5 . …

Two DNA bases, 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (hmC), marks of
epigenetic modification, are recognized in immobilized DNA strands and distinguished from G, A…

In this paper, we give an overview of our studies by static and time-resolved X-ray diffraction
of inverse cubic phases and phase transitions in lipids. In §1 , we briefly discuss the …

We describe the methods used in our laboratory for the analysis of single nucleic acid molecules
with protein nanopores. The technical section is preceded by a review of the variety of …

The ability to simultaneously monitor both the ionic current and fluorescence from membrane
proteins has the potential to link structural and functional changes in a protein. However, …

By making dynamic changes to the area of a droplet interface bilayer (DIB), we are able to
measure the specific capacitance of lipid bilayers with improved accuracy and precision over …

Ultra-rapid sequencing of DNA strands with nanopores is under intense investigation. The
αHL protein nanopore is a leading candidate sensor for this approach. Multiple base-…