Understanding the pharmacokinetics, blood compatibility, biodistribution and clearance
properties of nanoparticles is of great importance to their translation to clinical application. In this …

Cyclodextrin-based hydrogels were synthesized to create robust networks with tunable
mechanical properties capable of serving as device coatings. The CD networks were able to …

Objective. Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly
few studies characterizing the anatomy of the vagus nerve in large animal models as it …

Mosquitos are among the deadliest insects on the planet due to their ability to transmit
diseases like malaria through their bite. In order to bite, a mosquito must insert a set of micro-sized …

Intracortical microelectrodes have shown great success in enabling locked-in patients to
interact with computers, robotic limbs, and their own electrically driven limbs. The recent …

Electrical stimulation of the cervical vagus nerve using implanted electrodes (VNS) is FDA-approved
for the treatment of drug-resistant epilepsy, treatment-resistant depression, and …

Objective Clinical data suggest that efficacious vagus nerve stimulation (VNS) is limited by
side effects such as cough and dyspnea that have stimulation thresholds lower than those for …

Objective. Our objective was to determine how readily disruption of the blood–brain barrier (BBB)
occurred as a result of bone drilling during a craniotomy to implant microelectrodes in …

Trauma is the leading cause of death for people ages 1–44, with blood loss comprising 60–70%
of mortality in the absence of lethal CNS or cardiac injury. Immediate intervention is …

Implanted neural stimulation and recording devices hold vast potential to treat a variety of
neurological conditions, but the invasiveness, complexity, and cost of the implantation …