Dynamics of the mitochondrial permeability transition pore: Transient and permanent opening events

L Boyman, AK Coleman, G Zhao, AP Wescott… - Archives of biochemistry …, 2019 - Elsevier
… Liron Boyman a b , Andrew K. Coleman a b , Guiling Zhao a b , Andrew P. Wescott a b , …
(OMM), readily conducts small cations like Na + , K + and Ca 2+ through VDAC (the voltage …

Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle

AK Coleman, HC Joca, G Shi, WJ Lederer… - Journal of General …, 2021 - rupress.org
Microtubules tune cytoskeletal stiffness, which affects cytoskeletal mechanics and
mechanotransduction of striated muscle. While recent evidence suggests that microtubules enriched …

Quantitative tests reveal that microtubules tune the healthy heart but underlie arrhythmias in pathology

HC Joca, AK Coleman, CW Ward… - The Journal of …, 2020 - Wiley Online Library
Key points Our group previously discovered and characterized the microtubule
mechanotransduction pathway linking diastolic stretch to NADPH oxidase 2‐derived reactive oxygen …

Dry bedding provides cost-effective enrichment for group-housed rhesus macaques (Macaca mulatta)

…, N Morelli, S McAllister, K Coleman - Journal of the …, 2013 - ingentaconnect.com
Dry bedding has been shown to be an effective enrichment strategy for small groups of
captive nonhuman primates housed in cages or in small enclosures with concrete flooring. …

Camera-based Measurements of Intracellular [Na+] in Murine Atrial Myocytes

L Garber, HC Joca, AK Coleman, L Boyman… - JoVE (Journal of …, 2022 - jove.com
Intracellular sodium concentration ([Na+]i) is an important regulator of intracellular Ca2+. Its
study provides insight into the activation of the sarcolemmal Na+/Ca2+ exchanger, the …

Na+/K+ ATPase-Ca v 1.2 nanodomain differentially regulates intracellular [Na+],[Ca 2+] and local adrenergic signaling in cardiac myocytes

…, L Garber, HC Joca, N Verhoeven, AK Coleman… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Background The intracellular Na+ concentration ([Na+] i) is a crucial but understudied regulator
of cardiac myocyte function. The Na+/K+ ATPase (NKA) controls the steady-state [Na+] i …

[PDF][PDF] Microtubule Acetylation Regulates Striated Muscle Mechanotransduction

AK Coleman, HC Joca, G Shi, WJ Lederer, CW Ward - Biophysical Journal, 2020 - cell.com
In striated muscle, microtubules impact cytoskeletal stiffness to regulate mechanotransduction
through NADPH Oxidase 2 (Nox2) dependent reactive oxygen species (ROS) and calcium …

[PDF][PDF] Microtubule Acetylation Regulates Contractile Kinetics of Striated Muscle

AK Coleman, HC Joca, GSB Williams, WJ Lederer… - Biophysical …, 2019 - cell.com
Microtubules (MTs) are key cytoskeletal elements with many roles including protein trafficking,
defining cell shape, serving as signaling scaffolds, and providing a means for transmitting …

Common husbandry, housing, and animal care practices

K Coleman, G Timmel, K Prongay, KC Baker - Nonhuman primate welfare …, 2023 - Springer
Animal care in facilities housing nonhuman primates has undergone a transformation in the
past two decades, as the scientific community has learned more about the effects of …

HOLY CROSS JOURNAL OF LAW AND PUBLIC POLICY

…, K Andrew, F Baker, J Barry, E Briones, K Coleman… - HeinOnline
… Katherine Andrew Francis Baker John Barry Eugene Briones Katherine Coleman
Nicholas Delforto Nicholas DiMauro Patrick Donovan Wan Yi Fang Dolores Gaton …