User profiles for Andrew Martin Wright
Andrew Martin WrightPhD Student, Max Planck Institute for Biological Cybernetics, Eberhard Karls Universität … Verified email at tue.mpg.de Cited by 270 |
Contribution of macromolecules to brain 1H MR spectra: Experts' consensus recommendations
Proton MR spectra of the brain, especially those measured at short and intermediate echo
times, contain signals from mobile macromolecules (MM). A description of the main MM is …
times, contain signals from mobile macromolecules (MM). A description of the main MM is …
T2 relaxation times of macromolecules and metabolites in the human brain at 9.4 T
Purpose Relaxation times can contribute to spectral assignment. In this study, effective T 2
relaxation times ( ) of macromolecules are reported for gray and white matter–rich voxels in …
relaxation times ( ) of macromolecules are reported for gray and white matter–rich voxels in …
3D 31P MRSI of the human brain at 9.4 Tesla: Optimization and quantitative analysis of metabolic images
…, J Dorst, N Avdievitch, AM Wright… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To present 31 P whole brain MRSI with a high spatial resolution to probe quantitative
tissue analysis of 31 P MRSI at an ultrahigh field strength of 9.4 Tesla. Methods The study …
tissue analysis of 31 P MRSI at an ultrahigh field strength of 9.4 Tesla. Methods The study …
In vivo characterization of downfield peaks at 9.4 T: T2 relaxation times, quantification, pH estimation, and assignments
…, S Murali‐Manohar, AM Wright… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose Relaxation times are a valuable asset when determining spectral assignments. In
this study, apparent T 2 relaxation times ( ) of downfield peaks are reported in the human …
this study, apparent T 2 relaxation times ( ) of downfield peaks are reported in the human …
A novel method to measure T1‐relaxation times of macromolecules and quantification of the macromolecular resonances
Purpose Macromolecular peaks underlying metabolite spectra influence the quantification
of metabolites. Therefore, it is important to understand the extent of contribution from …
of metabolites. Therefore, it is important to understand the extent of contribution from …
Relaxation‐corrected macromolecular model enables determination of 1H longitudinal T1‐relaxation times and concentrations of human brain metabolites at 9.4T
Purpose Ultrahigh field MRS has improved characterization of the neurochemical profile. To
compare results obtained at 9.4T to those from lower field strengths, it is of interest to …
compare results obtained at 9.4T to those from lower field strengths, it is of interest to …
ProFit‐1D—A 1D fitting software and open‐source validation data sets
…, S Murali‐Manohar, J Dorst, AM Wright… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose Accurate and precise MRS fitting is crucial for metabolite concentration quantification
of 1 H‐MRS spectra. LCModel, a spectral fitting software, has shown to have certain …
of 1 H‐MRS spectra. LCModel, a spectral fitting software, has shown to have certain …
[HTML][HTML] Quantitative T1-relaxation corrected metabolite mapping of 12 metabolites in the human brain at 9.4 T
Magnetic resonance spectroscopic imaging (MRSI) is a non-invasive imaging modality that
enables observation of metabolites. Applications of MRSI for neuroimaging have shown …
enables observation of metabolites. Applications of MRSI for neuroimaging have shown …
Test–retest reproducibility of human brain multi‐slice 1H FID‐MRSI data at 9.4T after optimization of lipid regularization, macromolecular model, and spline baseline …
Purpose This study analyzes the effects of retrospective lipid suppression, a simulated
macromolecular prior knowledge and different spline baseline stiffness values on 9.4T multi‐slice …
macromolecular prior knowledge and different spline baseline stiffness values on 9.4T multi‐slice …
Dynamic observation of 2H labeled compounds in the human brain with 1H versus 2H magnetic resonance spectroscopy at 9.4T
L Ruhm, T Ziegs, AM Wright, CS Mathy… - bioRxiv, 2022 - biorxiv.org
The metabolic pathway of [6,6’- 2 H 2 ]-labeled glucose was investigated with two different
techniques. The first technique used direct detection of deuterium applying Deuterium …
techniques. The first technique used direct detection of deuterium applying Deuterium …