Innate lymphoid cells (ILCs) are a family of developmentally related cells that are involved
in immunity and in tissue development and remodelling. Recent research has identified …

Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified antigen
receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and are …

BACKGROUND Innate lymphoid cells (ILCs) are a growing family of immune cells that mirror
the phenotypes and functions of T cells. Natural killer (NK) cells can be considered the …

Innate immunity provides the first line of defence against invading pathogens and provides
important cues for the development of adaptive immunity. Type-2 immunity—responsible for …

ST2 is an IL-1 receptor family member with transmembrane (ST2L) and soluble (sST2)
isoforms. sST2 is a mechanically induced cardiomyocyte protein, and serum sST2 levels predict …

Naive CD4 + T cell differentiation into distinct subsets of T helper (Th) cells is a pivotal process
in the initiation of the adaptive immune response. Allergens predominantly stimulate Th2 …

Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their
development. We show that human ILC2s express skin homing receptors and infiltrate the skin …

… Jolin, Andrew NJ McKenzie; Identification of an interleukin (IL)-25–dependent cell population
… Bell and the McKenzie lab for critical reading of this manuscript and the MRC SABU/CBS …

Patients with asthma, a major public health problem, are at high risk for serious disease
from influenza virus infection, but the pathogenic mechanisms by which influenza A causes …

Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage that have
emerging roles in mediating immune responses and in regulating tissue homeostasis and …