Genetic mechanisms underlying age-related cognitive decline and dementia remain poorly
understood. Here, we take advantage of the Diversity Outbred mouse population to utilize …

Several studies report that caloric restriction (CR) or intermittent fasting (IF) can improve
cognition, while others report limited or no cognitive benefits. Here, we compare the effects of 20…

Many patients with Alzheimer's dementia (AD) also exhibit noncognitive symptoms such as
sensorimotor deficits, which can precede the hallmark cognitive deficits and significantly …

Periodontal disease is an age-associated disorder clinically defined by periodontal bone
loss, inflammation of the specialized tissues that surround and support the tooth, and …

Gram-negative bacteria use a needle-like protein assembly, the type III secretion apparatus,
to inject virulence factors into target cells to initiate human disease. The needle is formed by …

Alzheimer’s disease (AD), the leading cause of dementia, affects millions of people worldwide.
With no disease-modifying medication currently available, the human toll and economic …

An isochorismate–pyruvate lyase with adventitious chorismate mutase activity from
Pseudomonas aerugionsa (PchB) achieves catalysis of both pericyclic reactions in part by the …

Alzheimer’s disease (AD) is characterized by neurodegeneration, pathology accumulation,
and progressive cognitive decline. There is significant variation in age at onset and severity …

… differences were found between the liver and hepatoma enzymes (Ouellette, 1972); however,
it was noted that equivalent amounts of tRNA from these tissues differed in their extents of …

The inspection of welded and brazed joints has been performed in several industries using
ultrasonic phased array. In the automotive sector, many of the current standards for brazed …