Novel components of the Toxoplasma inner membrane complex revealed by BioID
AL Chen, EW Kim, JY Toh, AA Vashisht, AQ Rashoff… - MBio, 2015 - Am Soc Microbiol
The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to …
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to …
[HTML][HTML] PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism
Posterior fossa type A (PFA) ependymomas exhibit very low H3K27 methylation and
express high levels of EZHIP (Enhancer of Zeste Homologs Inhibitory Protein, also termed …
express high levels of EZHIP (Enhancer of Zeste Homologs Inhibitory Protein, also termed …
[PDF][PDF] H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2
SU Jain, AQ Rashoff, SD Krabbenhoft, D Hoelper… - Molecular cell, 2020 - cell.com
Diffuse midline gliomas and posterior fossa type A ependymomas contain the recurrent
histone H3 lysine 27 (H3 K27M) mutation and express the H3 K27M-mimic EZHIP (CXorf67), …
histone H3 lysine 27 (H3 K27M) mutation and express the H3 K27M-mimic EZHIP (CXorf67), …
[PDF][PDF] Novel components of the
AL Chen, EW Kim, JY Toh, AA Vashisht, AQ Rashoff… - 2015 - researchgate.net
The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to …
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to …
[HTML][HTML] The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
Mediator 12 (MED12) and MED13 are components of the Mediator multi-protein complex, that
facilitates the initial steps of gene transcription. Here, in an Arabidopsis mutant screen, we …
facilitates the initial steps of gene transcription. Here, in an Arabidopsis mutant screen, we …
Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail
…, S Kallappagoudar, CM Jablonowski, AJ Andrews… - Elife, 2021 - elifesciences.org
Sequencing of cancer genomes has identified recurrent somatic mutations in histones, termed
oncohistones, which are frequently poorly understood. Previously we showed that fission …
oncohistones, which are frequently poorly understood. Previously we showed that fission …
[HTML][HTML] Metabolic regulation of the epigenome drives lethal infantile ependymoma
Posterior fossa A (PFA) ependymomas are lethal malignancies of the hindbrain in infants and
toddlers. Lacking highly recurrent somatic mutations, PFA ependymomas are proposed to …
toddlers. Lacking highly recurrent somatic mutations, PFA ependymomas are proposed to …
[BOOK][B] Dysregulation of Polycomb Repressive Complex 2 by Oncogenic Histone Mutations in Pediatric Brain and Bone Tumors
S Jain - 2020 - search.proquest.com
In multicellular higher eukaryotes, a single zygotic gives rise to the formation of hundreds of
different tissues in the developed fetus through cellular differentiation. Each stage of cellular …
different tissues in the developed fetus through cellular differentiation. Each stage of cellular …
In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis
SM Nadipuram, EW Kim, AA Vashisht, AH Lin, HN Bell… - MBio, 2016 - Am Soc Microbiol
Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …
APEX2 proximity proteomics resolves flagellum subdomains and identifies flagellum tip-specific proteins in Trypanosoma brucei
DE Vélez-Ramírez, MM Shimogawa, SS Ray, A Lopez… - Msphere, 2021 - Am Soc Microbiol
Trypanosoma brucei is the protozoan parasite responsible for sleeping sickness, a lethal
vector-borne disease. T. brucei has a single flagellum (cilium) that plays critical roles in …
vector-borne disease. T. brucei has a single flagellum (cilium) that plays critical roles in …