Objective Rates of worsening and evolution to secondary progressive multiple sclerosis (MS)
may be substantially lower in actively treated patients compared to natural history studies …

Object Currently, mannitol is the recommended first choice for a hyperosmolar agent for use
in patients with elevated intracranial pressure (ICP). Some authors have argued that …

Of all the truncothalamic nuclei, the centromedian-parafascicular nuclei complex (CM-Pf) is
the largest and is considered the prototypic thalamic projection system. Located among the …

Importance Disability measures in multiple sclerosis (MS) fail to capture potentially important
variability in walking behavior. More sensitive and ecologically valid outcome measures are …

… Romeo, MD, Department of Neurology, University of Michigan, 1500 E. Medical Center
Drive, Floor 1, Reception C, Ann Arbor, MI 48109, USA. Tel: +1 734 232 0438; e-mail: [email …

In patients undergoing surgical resection of a metastatic brain tumor, whole brain radiation
therapy reduces the risk of recurrence and neurologic death. Focal radiation has the potential …

OBJECTIVE Despite numerous imaging studies highlighting the importance of the thalamus
in a patient’s surgical prognosis, human electrophysiological studies involving the limbic …

Background and Objectives The effects of the SARS-CoV-2 vaccination and infection on
clinical outcomes, including relapse risk, have been insufficiently explored in people with …

Background: Objective tools for prognosis and disease progression monitoring in multiple
sclerosis (MS) are lacking. The visuomotor system could be used to track motor dysfunction at …

Retrosigmoid craniotomy for microvascular decompression (MVD) has been traditionally
performed via craniectomy. Various closure techniques have been described, yet factors …