Primary triple-negative breast cancers (TNBCs), a tumour type defined by lack of oestrogen
receptor, progesterone receptor and ERBB2 gene amplification, represent approximately 16…

BACKGROUND As more oncology care is moved to the outpatient setting, the need for a
rapid means for oncologists to identify patients with significant distress has increased. …

Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and
behavioral research. Physiological similarity to mammals, ease of genetic manipulations, …

We conducted two studies with medically hospitalized cancer and acquired immunodeficiency
syndrome (AIDS) patients to assess the reliability and validity of a new measure of …

We introduce PyClone, a statistical model for inference of clonal population structures in
cancers. PyClone is a Bayesian clustering method for grouping sets of deeply sequenced …

Human cancers, including breast cancers, comprise clones differing in mutation content.
Clones evolve dynamically in space and time following principles of Darwinian evolution 1 , 2 , …

Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous cancer composed of
at least 2 molecular subtypes that differ in gene expression and distribution of mutations. …

In both speeches and interviews, speakers convey information and express opinions. In
speeches,, these activities are accomplished through direct monologue, unmediated by …

High‐grade serous ovarian cancer ( HGSC ) is characterized by poor outcome, often attributed
to the emergence of treatment‐resistant subclones. We sought to measure the degree of …

Background Germline truncating mutations in DICER1, an endoribonuclease in the RNase
III family that is essential for processing microRNAs, have been observed in families with the …