User profiles for Andrew S. Gaynor
Andrew GaynorPhD Candidate, University of Delaware Verified email at udel.edu Cited by 84 |
Cell-surface expression of neuron-glial antigen 2 (NG2) and melanoma cell adhesion molecule (CD146) in heterogeneous cultures of marrow-derived mesenchymal …
Cellular heterogeneity of mesenchymal stem cells (MSCs) impedes their use in regenerative
medicine. The objective of this research is to identify potential biomarkers for the …
medicine. The objective of this research is to identify potential biomarkers for the …
Synthetic biology approaches for targeted protein degradation
Protein degradation is an effective native mechanism used in modulating intracellular
information, and thus it plays an essential role in maintaining cellular homeostasis. Repurposing …
information, and thus it plays an essential role in maintaining cellular homeostasis. Repurposing …
Multiomics Characterization of a Less Invasive Microfluidic-Based Cell Sorting Technique
Fluorescence-activated cell sorting (FACS) is a specialized technique to isolate specific cell
subpopulations with a high level of recovery and accuracy. However, the cell sorting …
subpopulations with a high level of recovery and accuracy. However, the cell sorting …
Induced prodrug activation by conditional protein degradation
Enzyme prodrug therapies hold potential as a targeted treatment option for cancer patients.
However, off-target effects can be detrimental to patient health and represent a safety …
However, off-target effects can be detrimental to patient health and represent a safety …
Conditional Protein Rescue by Binding-Induced Protective Shielding
Synthetic protein-level circuits offer an extra layer of cellular control on top of conventional
gene-level circuits. Here, we describe a technology that allows conditional protein rescue (…
gene-level circuits. Here, we describe a technology that allows conditional protein rescue (…
[BOOK][B] Developing conditional protein rescue for synthetic proten-based logic circuits towards the detection and treatment of cancer
AS Gaynor - 2020 - search.proquest.com
Cancer is a complicated set of diseases marked by drastic changes in the cellular proteome.
To treat cancer, clinicians still strongly rely on chemotherapy, which kills mitotic cells …
To treat cancer, clinicians still strongly rely on chemotherapy, which kills mitotic cells …
Conditional Protein Rescue (CPR) by Binding-Induced Protective Shielding
An effective method to modulate the stability of proteins is essential to biological research.
Herein, we describe a new technology that allows conditional stabilization of proteins based …
Herein, we describe a new technology that allows conditional stabilization of proteins based …
Hate the course or hate to go: Semester differences in first year nursing attrition
S Andrew, Y Salamonson, R Weaver, A Smith… - Nurse education …, 2008 - Elsevier
Most of the attrition from nursing courses occurs in the first year of study. Devising university
strategies to reduce attrition requires an understanding of why students leave. The aim of …
strategies to reduce attrition requires an understanding of why students leave. The aim of …
A review of molybdenite, and fluorite mineralisation in Caledonian granite basement, western Ireland, incorporating new field and fluid inclusion studies, and Re-Os …
The recent discovery of late-magmatic quartz vein hosted molybdenite, and exceptional gem
quality vein fluorite, in the Caledonian Galway Granite Complex (GGC), has prompted a …
quality vein fluorite, in the Caledonian Galway Granite Complex (GGC), has prompted a …
Linguistic diversity as sociodemographic predictor of nursing program progression and completion
Attrition from undergraduate nursing programs continues to warrant investigation particularly
in the climate of nursing shortages and fiscal reflection on academic institutional programs. …
in the climate of nursing shortages and fiscal reflection on academic institutional programs. …