Accurate prediction of protein structures and interactions using a three-track neural network
…, H Park, C Adams, CR Glassman, A DeGiovanni… - Science, 2021 - science.org
DeepMind presented notably accurate predictions at the recent 14th Critical Assessment of
Structure Prediction (CASP14) conference. We explored network architectures that …
Structure Prediction (CASP14) conference. We explored network architectures that …
[HTML][HTML] Jungle Express is a versatile repressor system for tight transcriptional control
TL Ruegg, JH Pereira, JC Chen, A DeGiovanni… - Nature …, 2018 - nature.com
Tightly regulated promoters are essential for numerous biological applications, where strong
inducibility, portability, and scalability are desirable. Current systems are often incompatible …
inducibility, portability, and scalability are desirable. Current systems are often incompatible …
[PDF][PDF] Structure of a three-domain sesquiterpene synthase: a prospective target for advanced biofuels production
RP McAndrew, PP Peralta-Yahya, A DeGiovanni… - Structure, 2011 - cell.com
The sesquiterpene bisabolene was recently identified as a biosynthetic precursor to bisabolane,
an advanced biofuel with physicochemical properties similar to those of D2 diesel. High-…
an advanced biofuel with physicochemical properties similar to those of D2 diesel. High-…
A synthetic gene library yields a previously unknown glycoside phosphorylase that degrades and assembles poly-β-1, 3-GlcNAc, completing the suite of β-linked …
…, JH Pereira, F Liu, G Tegl, A DeGiovanni… - ACS central …, 2022 - ACS Publications
The considerable utility of glycoside phosphorylases (GPs) has led to substantial efforts over
the past two decades to expand the breadth of known GP activities. Driven largely by the …
the past two decades to expand the breadth of known GP activities. Driven largely by the …
Crystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implications
JS Kim, A DeGiovanni, J Jancarik… - Proceedings of the …, 2005 - National Acad Sciences
Type I restriction-modification enzymes are differentiated from type II and type III enzymes
by their recognition of two specific dsDNA sequences separated by a given spacer and …
by their recognition of two specific dsDNA sequences separated by a given spacer and …
Crystal structure of the multidrug efflux transporter AcrB at 3.1 Å resolution reveals the N-terminal region with conserved amino acids
…, I Ankoudinova, C Huang, Y Lou, A DeGiovanni… - Journal of structural …, 2007 - Elsevier
Crystal structures of the bacterial multidrug transporter AcrB in R32 and C2 space groups
showing both symmetric and asymmetric trimeric assemblies, respectively, supplemented with …
showing both symmetric and asymmetric trimeric assemblies, respectively, supplemented with …
[HTML][HTML] Plant cell wall glycosyltransferases: High-throughput recombinant expression screening and general requirements for these challenging enzymes
DH Welner, D Shin, GP Tomaleri, AM DeGiovanni… - PloS one, 2017 - journals.plos.org
Molecular characterization of plant cell wall glycosyltransferases is a critical step towards
understanding the biosynthesis of the complex plant cell wall, and ultimately for efficient …
understanding the biosynthesis of the complex plant cell wall, and ultimately for efficient …
Structural genomics of minimal organisms and protein fold space
…, BA Martinez, N Oganesyan, A DeGiovanni… - Journal of Structural and …, 2005 - Springer
The initial aim of the Berkeley Structural Genomics Center is to obtain a near-complete
structural complement of two minimal organisms, closely related pathogens Mycoplasma …
structural complement of two minimal organisms, closely related pathogens Mycoplasma …
A highly active Burkholderia polyketoacyl-CoA thiolase for production of triacetic acid lactone
Triacetic acid lactone (TAL) is a platform chemical biosynthesized primarily through
decarboxylative Claisen condensation by type III polyketide synthase 2-pyrone synthase (2-PS). …
decarboxylative Claisen condensation by type III polyketide synthase 2-pyrone synthase (2-PS). …
[HTML][HTML] X-ray diffraction analysis and in vitro characterization of the UAM2 protein from Oryza sativa
DH Welner, AYL Tsai, AM DeGiovanni… - … Section F: Structural …, 2017 - scripts.iucr.org
The role of seemingly non-enzymatic proteins in complexes interconverting UDP-arabinopyranose
and UDP-arabinofuranose (UDP-arabinosemutases; UAMs) in the plant cytosol …
and UDP-arabinofuranose (UDP-arabinosemutases; UAMs) in the plant cytosol …