Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib

…, V Saada, S Alsafadi, MS Vijayabaskar, A Peniket… - Nature medicine, 2018 - nature.com
Mutations in the gene encoding isocitrate dehydrogenase 2 (IDH2) occur in several types of
cancer, including acute myeloid leukemia (AML). In model systems, mutant IDH2 causes …

Evidence for reduced B-cell progenitors in early (low-risk) myelodysplastic syndrome

A Sternberg, S Killick, T Littlewood, C Hatton, A Peniket… - Blood, 2005 - ashpublications.org
Early, low-risk International Prognostic Scoring System (IPSS) myelodysplastic syndrome (MDS)
is a heterogeneous disorder where the molecular and cellular hematopoietic defects …

Reduced‐intensity conditioning with fludarabine and busulfan versus fludarabine and melphalan for patients with acute myeloid leukemia: A report from the A cute L …

F Baron, M Labopin, A Peniket, P Jindra, B Afanasyev… - Cancer, 2015 - Wiley Online Library
BACKGROUND Fludarabine plus busulfan (FB) and fludarabine plus melphalan (FM) are 2
widely used reduced‐intensity conditioning (RIC) regimens for allogeneic hematopoietic …

Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation: a retrospective cohort study

…, A Patel, K Patrick, B Pedron, A Peniket… - The Lancet …, 2020 - thelancet.com
Background The success of unrelated haemopoietic cell transplantation (HCT) is limited by
graft-versus-host disease (GVHD), which is the main post-transplantation challenge when …

Assessing the impact of lockdown: Fresh challenges for the care of haematology patients in the COVID‐19 pandemic.

…, S Pavord, GP Collins, A Peniket - British journal of …, 2020 - search.ebscohost.com
… Collins2 Andy Peniket2 … Willan J, King AJ, Hayes S, Collins GP, Peniket A. Care of
haematology patients in a COVID-19 epidemic. Br J Haematol. …

Genomic surveillance of Escherichia coli and Klebsiella spp. in hospital sink drains and patients

…, S Lipworth, HS Gweon, A Peniket… - Microbial …, 2020 - microbiologyresearch.org
Escherichia coli and Klebsiella spp. are important human pathogens that cause a wide
spectrum of clinical disease. In healthcare settings, sinks and other wastewater sites have been …

[HTML][HTML] Impaired antibody response to COVID‐19 vaccination in patients with chronic myeloid neoplasms

…, K Jeffery, AJ Mead, A Peniket… - British Journal of …, 2021 - ncbi.nlm.nih.gov
The COVID-19 pandemic has had a severe impact on people with blood cancers. Patients
with blood cancer are at an increased risk of poor outcomes after COVID-19 infection, with …

Regional outcomes of severe acute respiratory syndrome coronavirus 2 infection in hospitalised patients with haematological malignancy

…, S Prideaux, GP Collins, A Peniket - European journal of …, 2020 - Wiley Online Library
Objectives We sought to characterise the outcomes of patients with haematological
malignancy and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection in …

[HTML][HTML] Systematic review of patient-reported outcome measures in graft-versus-host disease

…, A Scherwath, AB Badiella, A Peniket… - Biology of Blood and …, 2020 - Elsevier
Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic
stem cell transplantation. These patients face a unique challenge due to the complexity of …

Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia

…, AR Lucena-Araujo, F Traina, A Peniket… - Blood …, 2020 - ashpublications.org
The 2017 European LeukemiaNet 2017 acute myeloid leukemia (AML) risk stratification (ELN2017)
is widely used for risk-stratifying patients with AML. However, its applicability in low- …