Alzheimer’s disease (AD) is the most common form of dementia in the elderly. According to
the amyloid hypothesis, the accumulation and deposition of amyloid-beta (Aβ) peptides play …

Background Alzheimer’s disease (AD) is an incurable neurodegenerative disorder
characterised by the progressive buildup of toxic amyloid-beta (Aβ) and tau protein aggregates …

The combination of chemogenetics targeting specific brain cell populations with in vivo
imaging techniques provides scientists with a powerful new tool to study functional neural …

Alzheimer’s disease (AD), the most common type of dementia, is an incurable brain disorder
characterised by the progressive build-up of toxic amyloid-beta (Aβ) and tau protein …

Noninvasive monitoring of intracellular targets such as enzymes, receptors, or mRNA by
means of magnetic resonance imaging (MRI) is increasingly gaining relevance in various …

Here we report on a dual‐modal 19 F and 1 H MRI paramagnetic probe with a self‐immolative
linker, Gd–DOMF–Gal. The enzymatic conversion of this probe by β‐galactosidase …

… for mouse i at time point j and t ij corresponds to the time at which mouse i at time point j is
scored. The error term ε ij corresponds to the error in measurement for mouse i at time j and is …

Regions of brain activation related to movements in the running-wheel as revealed by increased
intensity of T1-weighted images due to Mn2+ accumulation in runners (n= 6) compared …

Micron-sized paramagnetic iron oxide particles (MPIO) are commonly used as contrast
agents in magnetic resonance imaging (MRI) that produce negative contrast enhancement, ie …

… To Ulrich, Aneta & Ilgar. Without you this would not have been possible. … Aneta Keliris and
Dr. Matteo Placidi for their advice about science, research and for sharing their experience …