Circulating proteins are vital in human health and disease and are frequently used as biomarkers
for clinical decision-making or as targets for pharmacological intervention. By mapping …

The ever more complex and larger datasets that statisticians can routinely access have
prompted the modi cation of traditional statistical methodology. Notably, genomic data have …

Owing to a technical problem, the below authors were missing from the author list in the
originally published version of this Article. Further, the full information on the authors’ …

Age at first sexual intercourse and age at first birth have implications for health and
evolutionary fitness. In this genome-wide association study (age at first sexual intercourse, N = …

Background Molecular multi-omics data provide an in-depth view on biological systems, and
their integration is crucial to gain insights in complex regulatory processes. These data can …

The timing of reproductive behaviour – age at first sexual intercourse (AFS) and age at first
birth (AFB) – has implications for reproductive health, adolescent development and …

Gene regulation in eukaryotes is profoundly shaped by the 3D organization of chromatin within
the cell nucleus. Distal regulatory interactions between enhancers and their target genes …

With an estimated prevalence of 463 million affected, type 2 diabetes represents a major
challenge to health care systems worldwide. Analyzing the plasma proteomes of individuals …

Age at first sexual intercourse (AFS) and age at first birth (AFB) have implications for health
and evolutionary fitness. In the largest genome-wide association study to date (AFS, N= …

1 Supplements Genetic identification of two novel loci associated with steroid-sensitive
nephrotic syndrome 1 Stephanie Dufek*, Page 1 1 Supplements Genetic identification of two …