User profiles for Angela Meccariello
Angela MeccarielloImperial College London, Department of Life Sciences Verified email at imperial.ac.uk Cited by 543 |
[HTML][HTML] Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes
A Meccariello, SM Monti, A Romanelli, R Colonna… - Scientific reports, 2017 - nature.com
The Mediterranean fruitfly Ceratitis capitata (medfly) is an invasive agricultural pest of high
economic impact and has become an emerging model for developing new genetic control …
economic impact and has become an emerging model for developing new genetic control …
[HTML][HTML] CRISPR-Cas9 targeted disruption of the yellow ortholog in the housefly identifies the brown body locus
SD Heinze, T Kohlbrenner, D Ippolito, A Meccariello… - Scientific reports, 2017 - nature.com
The classic brown body (bwb) mutation in the housefly Musca domestica impairs normal
melanization of the adult cuticle. In Drosophila melanogaster, a reminiscent pigmentation defect …
melanization of the adult cuticle. In Drosophila melanogaster, a reminiscent pigmentation defect …
Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests
In insects, rapidly evolving primary sex-determining signals are transduced by a conserved
regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (…
regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (…
[HTML][HTML] Engineered sex ratio distortion by X-shredding in the global agricultural pest Ceratitis capitata
A Meccariello, F Krsticevic, R Colonna, G Del Corsano… - BMC biology, 2021 - Springer
Background Genetic sex ratio distorters are systems aimed at effecting a bias in the
reproductive sex ratio of a population and could be applied for the area-wide control of sexually …
reproductive sex ratio of a population and could be applied for the area-wide control of sexually …
[HTML][HTML] A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters
B Fasulo, A Meccariello, M Morgan, C Borufka… - PLoS …, 2020 - journals.plos.org
Synthetic sex distorters have recently been developed in the malaria mosquito, relying on
endonucleases that target the X-chromosome during spermatogenesis. Although inspired by …
endonucleases that target the X-chromosome during spermatogenesis. Although inspired by …
[HTML][HTML] Next-generation genetic sexing strain establishment in the agricultural pest Ceratitis capitata
Tephritid fruit fly pests pose an increasing threat to the agricultural industry due to their
global dispersion and a highly invasive nature. Here we showcase the feasibility of an early-…
global dispersion and a highly invasive nature. Here we showcase the feasibility of an early-…
[HTML][HTML] The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a …
Background The Mediterranean fruit fly (medfly), Ceratitis capitata, is a major destructive
insect pest due to its broad host range, which includes hundreds of fruits and vegetables. It …
insect pest due to its broad host range, which includes hundreds of fruits and vegetables. It …
[HTML][HTML] Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata
A Meccariello, S Hou, S Davydova, JD Fawcett… - Nature …, 2024 - nature.com
Homing-based gene drives are recently proposed interventions promising the area-wide,
species-specific genetic control of harmful insect populations. Here we characterise a first set …
species-specific genetic control of harmful insect populations. Here we characterise a first set …
Syntopic Cystoseira taxa support different molluscan assemblages in the Gulf of Naples (southern Tyrrhenian Sea)
…, I Bertocci, S Fioretti, A Meccariello… - Marine and …, 2019 - CSIRO Publishing
Brown macroalgae belonging to the genus Cystoseira (Fucales: Sargassaceae) are canopy-forming
organisms the recent decline of which at a basin and local scale has been widely …
organisms the recent decline of which at a basin and local scale has been widely …
Targeted somatic mutagenesis through CRISPR/Cas9 ribonucleoprotein complexes in the olive fruit fly, Bactrocera oleae
A Meccariello, KT Tsoumani, A Gravina… - Archives of Insect …, 2020 - Wiley Online Library
The olive fruit fly, Bactrocera oleae (Diptera: Tephritidae), is the most destructive insect pest
of olive cultivation, causing significant economic and production losses. Here, we present …
of olive cultivation, causing significant economic and production losses. Here, we present …