Single-cell sequencing studies have characterized the transcriptomic signature of cell types
within the kidney. However, the spatial distribution of acute kidney injury (AKI) is regional …

Uromodulin (or Tamm-Horsfall protein) is a glycoprotein uniquely produced in the kidney by
tubular cells of the thick ascending limb of the loop of Henle and early distal tubules. This …

The human kidney is a complex organ with various cell types that are intricately organized
to perform key physiological functions and maintain homeostasis. New imaging modalities, …

There is a need to define regions of gene activation or repression that control human kidney
cells in states of health, injury, and repair to understand the molecular pathogenesis of …

Kidney stone disease causes significant morbidity and increases health care utilization. In
this work, we decipher the cellular and molecular niche of the human renal papilla in patients …

Kidney stone disease causes significant morbidity and increases health care utilization. The
pathogenesis of stone disease is not completely understood, due in part to the poor …

The advent of personalized medicine has driven the development of novel approaches for
obtaining detailed cellular and molecular information from clinical tissue samples. Tissue …

Uromodulin [Tamm-Horsfall protein (THP)] is a glycoprotein uniquely produced in the kidney.
It is released by cells of the thick ascending limbs apically in the urine and basolaterally in …

Label‐free fluorescence imaging of kidney sections can provide important morphological
information, but its utility has not been tested in a histology processing workflow. We tested the …

The kidney is a complex organ and a key regulator of homeostasis. It comprises various
functional units (nephrons, vasculature, and interstitium) that are organized spatially, so that …