Spinal cord perfusion pressure predicts neurologic recovery in acute spinal cord injury

JW Squair, LM Bélanger, A Tsang, L Ritchie… - Neurology, 2017 - AAN Enterprises
Objective: To determine whether spinal cord perfusion pressure (SCPP) as measured with a
lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the …

Combined immunodeficiency associated with homozygous MALT1 mutations

…, JJ Priatel, R Tan, C Senger, A Tsang… - Journal of allergy and …, 2014 - jacionline.org
From athe University Children’s Hospital at Dr von Haunersches Kinderspital and the
Departments of bOphthalmology, cPathology, and dDermatology and Allergology, Ludwig …

Predicting injury severity and neurological recovery after acute cervical spinal cord injury: a comparison of cerebrospinal fluid and magnetic resonance imaging …

…, K Dong, L Belanger, L Ritchie, A Tsang… - Journal of …, 2018 - liebertpub.com
Biomarkers of acute human spinal cord injury (SCI) could provide a more objective measure
of spinal cord damage and a better predictor of neurological outcome than current …

Empirical targets for acute hemodynamic management of individuals with spinal cord injury

JW Squair, LM Bélanger, A Tsang, L Ritchie… - Neurology, 2019 - AAN Enterprises
Objective To determine the hemodynamic conditions associated with optimal neurologic
improvement in individuals with acute traumatic spinal cord injury (SCI) who had lumbar …

Association of CSF and serum neurofilament light and glial fibrillary acidic protein, Injury Severity, and Outcome in spinal cord Injury

…, MA Skinnider, L Belanger, L Ritchie, A Tsang… - Neurology, 2023 - AAN Enterprises
Background and Objectives Traumatic spinal cord injury (SCI) is highly heterogeneous, and
tools to better delineate pathophysiology and recovery are needed. Our objective was to …

A targeted proteomics analysis of cerebrospinal fluid after acute human spinal cord injury

…, A Prudova, L Belanger, L Ritchie, A Tsang… - Journal of …, 2017 - liebertpub.com
Efforts to validate novel therapies in acute clinical trials for spinal cord injury (SCI) are impeded
by the lack of objective quantitative measures that reflect injury severity and accurately …

[HTML][HTML] Proteomic portraits reveal evolutionarily conserved and divergent responses to spinal cord injury

…, F Streijger, L Belanger, L Ritchie, A Tsang… - Molecular & Cellular …, 2021 - ASBMB
Despite the emergence of promising therapeutic approaches in preclinical studies, the failure
of large-scale clinical trials leaves clinicians without effective treatments for acute spinal …

Characterization of cerebrospinal fluid ubiquitin C-terminal hydrolase L1 as a biomarker of human acute traumatic spinal cord injury

…, J Cooper, L Belanger, L Ritchie, A Tsang… - Journal of …, 2021 - liebertpub.com
A major obstacle for translational research in acute spinal cord injury (SCI) is the lack of
biomarkers that can objectively stratify injury severity and predict outcome. Ubiquitin C-terminal …

Two Distinct Receptors Mediate Nonopsonic Phagocytosis of Different Strains of Pseudomonas aeruginosa

…, RW Stokes, D Simpson, A Tsang… - The Journal of …, 2001 - academic.oup.com
Complement receptor 3 (CR3) mediates both opsonic and nonopsonic phagocytosis of bacteria.
Leukocyte adhesion deficiency (LAD) allows for the study of CR3-dependent phagocyte-…

Clinical and laboratory features associated with myeloperoxidase expression in pediatric B‐lymphoblastic leukemia

…, AF Setiadi, L Liu, A Tsang… - Cytometry Part B …, 2021 - Wiley Online Library
Background B‐lymphoblastic leukemia (B‐ALL) is the most common childhood malignancy,
and its diagnosis requires immunophenotypically demonstrating blast B cell lineage …