Objective The aim of this study was to analyse the clinical characteristics of acute pancreatitis
(AP) in a prospectively collected, large, multicentre cohort and to validate the major …

The aim of the study was to demonstrate that the bZIP-type transcription factor AtfA regulates
different types of stress responses in Aspergillus nidulans similarly to Atf1, the orthologous ‘…

Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
variants of concern (VOCs) Alpha and Delta are more transmissible, infectious…

Mucus plugging constitutes a nutrient‐rich nidus for a bacterial infection that has long been
recognized as a potent stimulus for neutrophilic airway inflammation driving progressive lung …

Aquaporins (AQPs) facilitate the transepithelial water flow involved in epithelial fluid secretion
in numerous tissues; however, their function in the pancreas is less characterized. Acute …

The solute carrier family 26, member 9 (SLC26A9) is an epithelial chloride channel that is
expressed in several organs affected in patients with cystic fibrosis (CF) including the lungs, …

Objective Biomedical investment trends in 2015 show a huge decrease of investment in
gastroenterology. Since academic research usually provides the basis for industrial research …

CFTR modulator therapy with elexacaftor/tezacaftor/ivacaftor (ETI) has been approved for
people with CF and at least one F508del allele in Europe. In the US, the ETI label has been …

The nasal epithelium represents the first line of defense against inhaled pathogens, allergens,
and irritants and plays a key role in the pathogenesis of a spectrum of acute and chronic …

Objective: Defective mucus production in the pancreas may be an important factor in the
initiation and progression of chronic pancreatitis (CP), therefore we aimed to (i) investigate the …