These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical aspects of …

Interleukin (IL)-17-producing T helper cells (T H 17) are a recently identified CD4 + T cell
subset distinct from T helper type 1 (T H 1) and T helper type 2 (T H 2) cells 1 . T H 17 cells can …

▪ Abstract In vertebrates, serum antibodies are an essential component of innate and
adaptive immunity and immunological memory. They also can contribute significantly to …

From a technical point of view a flow cytometer is a light detection device capable of detecting
photons of different wavelengths over a high dynamic range. In order to achieve a high …

Recent results suggest that plasma cell longevity is not an intrinsic capacity, but depends on
yet unknown factors produced in their environment. In this study, we show that the cytokines …

Background La/SSB is a phosphoprotein that associates with various small RNA molecules.
It has been found that the primary phosphorylation site of the molecule during various …

Plasma blasts formed during memory immune responses emigrate from the spleen to migrate
into the bone marrow and into chronically inflamed tissues where they differentiate into …

Aberrant production of autoantibodies by inappropriately self-reactive plasma cells is an
inherent characteristic of autoimmune diseases. Several therapeutic strategies aim to deplete …

Proliferation, mutation, and selection in the germinal center (GC) are thought to occur in
distinct microanatomical compartments—the dark zone (DZ) and the light zone (LZ). Thus, …

COVID-19-induced "acute respiratory distress syndrome" (ARDS) is associated with prolonged
respiratory failure and high mortality, but the mechanistic basis of lung injury remains …