Objective The study is aimed at widening the clinical and genetic spectrum and at assessing
genotype-phenotype associations in QARS encephalopathy. Methods Through diagnostic …

Aberrant protein aggregation is a pathological cellular hallmark of many neurodegenerative
diseases, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD), where the …

Background Deciphering the monogenetic causes of neurodevelopmental disorders (NDD)
is an important milestone to offer personalized care. But the plausibility of reported candidate …

We conducted preregistered replications of 28 classic and contemporary published findings,
with protocols that were peer reviewed in advance, to examine variation in effect …

d-cycloserine (DCS) – augmented exposure therapy has proven efficacy in the treatment of
acrophobia, social phobia, panic disorder and OCD. Here we studied whether DCS can also …

Background/Objective The aim of this study was to investigate whether the three resource
variables sense of coherence, resilience, and dispositional optimism become impaired when …

Importance Whether and under which conditions D-cycloserine (DCS) augments the effects
of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and …

Background & Aims An increased number of macrophages in adipose tissue is associated
with insulin resistance and metabolic dysfunction in obese people. However, little is known …

Importance Sepsis is a common syndrome with substantial morbidity and mortality. A combination
of vitamin C, thiamine, and corticosteroids has been proposed as a potential treatment …

Importance Sepsis is associated with long-term cognitive impairment and worse psychological
and functional outcomes. Potential mechanisms include intracerebral oxidative stress and …