Background Cell-free tumor-derived DNA (ctDNA) allows non-invasive monitoring of
cancers, but its utility in renal cell cancer (RCC) has not been established. Methods Here, a …

Long-lasting success in lung cancer therapy using tyrosine kinase inhibitors (TKIs) is rare
since the tumors develop resistance due to the occurrence of molecularly altered subclones. …

Simple Summary Liquid biopsies provide a non-invasive means to diagnose and profile
tumors when tissue is not available. Sequence-based analysis of cell-free DNA (cfDNA) is …

Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific antigen…

Background DNA methylation (5-mC) signals in cell-free DNA (cfDNA) of cancer patients
represent promising biomarkers for minimally invasive tumor detection. The high abundance of …

The availability of tyrosine kinase inhibitors (TKI) during the past ten years has led to improved
response and overall survival of patients suffering from metastatic clear cell renal cell …

Recently, many genome‐wide profiling studies provided insights into the molecular make‐up
of major cancer types. The deeper understanding of these genetic alterations and their …

Faces are widely used as stimuli in various research fields. Interest in emotion-related
differences and age-associated changes in the processing of faces is growing. With the aim of …

A family of dinuclear complexes was rationally designed to bind to two neighboring phosphate
diesters of DNA by molecular recognition. Although these complexes bind strongly and …

Two studies investigated the overpowering hypothesis as a possible explanation for the
currently inconclusive empirical picture on age differences in affective responding to unpleasant …