Recent characterisations of self-organising systems depend upon the presence of a ‘Markov
blanket’: a statistical boundary that mediates the interactions between the inside and …

There is a steadily growing literature on the role of the immune system in psychiatric
disorders. So far, these advances have largely taken the form of correlations between specific …

Integrating neurons into digital systems may enable performance infeasible with silicon alone.
Here, we develop DishBrain, a system that harnesses the inherent adaptive computation …

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of cancers.
Collectively, HNSCC ranks sixth in incidence rate worldwide. Apart from classical risk factors …

The burden of large and rare copy number genetic variants (CNVs) as well as certain specific
CNVs increase the risk of developing schizophrenia. Several cognitive measures are …

Aim: To investigate export of Hedgehog pathway (Hh) proteins Patched1, Smoothened, Sonic
hedgehog and Indian hedgehog in cervical cancer cell line (CaCx) exosomes. Methods: …

Exosomes are cell-secreted nanovesicles present in biological fluids in normal and diseased
conditions. Owing to their seminal role in cell–cell communication, emerging evidences …

Hematopoietic stem cell (HSC) gene therapy has curative potential; however, its use is limited
by the morbidity and mortality associated with current chemotherapy-based conditioning. …

Background Angiogenic switch is a hallmark feature of transition from low-grade to high-grade
cervical intraepithelial neoplasia (CIN) in cervical cancer progression. Therefore, early …

Among countries with river basin organizations to manage their water resources, Spain's
experience is one of the longest. One of the first basin agencies established in Spain was for …