[HTML][HTML] Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus macaque (Macaca mulatta) model

MR Koenig, AM Mitzey, X Zeng, L Reyes… - PLoS …, 2023 - journals.plos.org
Zika virus (ZIKV) can be transmitted vertically from mother to fetus during pregnancy, resulting
in a range of outcomes including severe birth defects and fetal/infant death. Potential …

[HTML][HTML] Previous exposure to dengue virus is associated with increased Zika virus burden at the maternal-fetal interface in rhesus macaques

…, JM Hayes, JC Eickhoff, AM Mitzey… - PLoS neglected …, 2021 - journals.plos.org
Concerns have arisen that pre-existing immunity to dengue virus (DENV) could enhance Zika
virus (ZIKV) disease, due to the homology between ZIKV and DENV and the observation of …

African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques

…, MK Fritsch, JM Hayes, JC Eickhoff, AM Mitzey… - Journal of …, 2021 - Am Soc Microbiol
Following the Zika virus (ZIKV) outbreak in the Americas, ZIKV was causally associated with
microcephaly and a range of neurological and developmental symptoms, termed congenital …

[HTML][HTML] Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus

…, SJ Havlicek, S Kabakov, AM Mitzey… - PLoS neglected …, 2022 - journals.plos.org
Countermeasures against Zika virus (ZIKV), including vaccines, are frequently tested in
nonhuman primates (NHP). Macaque models are important for understanding how ZIKV …

[HTML][HTML] Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model

…, EK Bohm, JC Pritchard, AM Weiler, AM Mitzey… - Frontiers in …, 2023 - frontiersin.org
Introduction Zika virus (ZIKV) infection during pregnancy results in a spectrum of birth
defects and neurodevelopmental deficits in prenatally exposed infants, with no clear …

[HTML][HTML] Neonatal development in prenatally Zika virus-exposed infant macaques with dengue immunity

K Ausderau, S Kabakov, E Razo, AM Mitzey, KM Bach… - Viruses, 2021 - mdpi.com
Infants exposed to Zika virus (ZIKV) prenatally may develop birth defects, developmental
deficits, or remain asymptomatic. It is unclear why some infants are more affected than others, …

Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and …

RM Novick, AM Mitzey, MS Brownfield… - Journal of Pharmacology …, 2009 - ASPET
Flavin-containing monooxygenases (FMOs) play significant roles in the metabolism of drugs
and endogenous or foreign compounds. In this study, the regional distribution of FMO …

[HTML][HTML] Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an …

MR Koenig, AM Mitzey, TK Morgan, X Zeng… - PloS one, 2023 - journals.plos.org
Background Congenital Zika virus (ZIKV) infection can result in birth defects, including
malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: …

[HTML][HTML] Decidual leukocytes respond to African lineage Zika virus infection with mild anti-inflammatory changes during acute infection in rhesus macaques

…, J Vazquez, FB Leyva Jaimes, AM Mitzey… - Frontiers in …, 2024 - frontiersin.org
Zika virus (ZIKV) can be vertically transmitted during pregnancy resulting in a range of
adverse pregnancy outcomes. The decidua is commonly found to be infected by ZIKV, yet the …

RT-PCR-based tyrosine kinase display profiling of canine melanoma: IGF-1 receptor as a potential therapeutic target

DH Thamm, MK Huelsmeyer, AM Mitzey… - Melanoma …, 2010 - journals.lww.com
Canine malignant melanoma (CMM) resembles human malignant melanoma in terms of
metastatic behavior, refractoriness to standard therapy, and tumor antigen expression but it is …