[HTML][HTML] Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus macaque (Macaca mulatta) model
MR Koenig, AM Mitzey, X Zeng, L Reyes… - PLoS …, 2023 - journals.plos.org
Zika virus (ZIKV) can be transmitted vertically from mother to fetus during pregnancy, resulting
in a range of outcomes including severe birth defects and fetal/infant death. Potential …
in a range of outcomes including severe birth defects and fetal/infant death. Potential …
[HTML][HTML] Previous exposure to dengue virus is associated with increased Zika virus burden at the maternal-fetal interface in rhesus macaques
…, JM Hayes, JC Eickhoff, AM Mitzey… - PLoS neglected …, 2021 - journals.plos.org
Concerns have arisen that pre-existing immunity to dengue virus (DENV) could enhance Zika
virus (ZIKV) disease, due to the homology between ZIKV and DENV and the observation of …
virus (ZIKV) disease, due to the homology between ZIKV and DENV and the observation of …
African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques
…, MK Fritsch, JM Hayes, JC Eickhoff, AM Mitzey… - Journal of …, 2021 - Am Soc Microbiol
Following the Zika virus (ZIKV) outbreak in the Americas, ZIKV was causally associated with
microcephaly and a range of neurological and developmental symptoms, termed congenital …
microcephaly and a range of neurological and developmental symptoms, termed congenital …
[HTML][HTML] Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus
…, SJ Havlicek, S Kabakov, AM Mitzey… - PLoS neglected …, 2022 - journals.plos.org
Countermeasures against Zika virus (ZIKV), including vaccines, are frequently tested in
nonhuman primates (NHP). Macaque models are important for understanding how ZIKV …
nonhuman primates (NHP). Macaque models are important for understanding how ZIKV …
[HTML][HTML] Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model
…, EK Bohm, JC Pritchard, AM Weiler, AM Mitzey… - Frontiers in …, 2023 - frontiersin.org
Introduction Zika virus (ZIKV) infection during pregnancy results in a spectrum of birth
defects and neurodevelopmental deficits in prenatally exposed infants, with no clear …
defects and neurodevelopmental deficits in prenatally exposed infants, with no clear …
[HTML][HTML] Neonatal development in prenatally Zika virus-exposed infant macaques with dengue immunity
Infants exposed to Zika virus (ZIKV) prenatally may develop birth defects, developmental
deficits, or remain asymptomatic. It is unclear why some infants are more affected than others, …
deficits, or remain asymptomatic. It is unclear why some infants are more affected than others, …
Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and …
RM Novick, AM Mitzey, MS Brownfield… - Journal of Pharmacology …, 2009 - ASPET
Flavin-containing monooxygenases (FMOs) play significant roles in the metabolism of drugs
and endogenous or foreign compounds. In this study, the regional distribution of FMO …
and endogenous or foreign compounds. In this study, the regional distribution of FMO …
[HTML][HTML] Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an …
MR Koenig, AM Mitzey, TK Morgan, X Zeng… - PloS one, 2023 - journals.plos.org
Background Congenital Zika virus (ZIKV) infection can result in birth defects, including
malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: …
malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: …
[HTML][HTML] Decidual leukocytes respond to African lineage Zika virus infection with mild anti-inflammatory changes during acute infection in rhesus macaques
…, J Vazquez, FB Leyva Jaimes, AM Mitzey… - Frontiers in …, 2024 - frontiersin.org
Zika virus (ZIKV) can be vertically transmitted during pregnancy resulting in a range of
adverse pregnancy outcomes. The decidua is commonly found to be infected by ZIKV, yet the …
adverse pregnancy outcomes. The decidua is commonly found to be infected by ZIKV, yet the …
RT-PCR-based tyrosine kinase display profiling of canine melanoma: IGF-1 receptor as a potential therapeutic target
DH Thamm, MK Huelsmeyer, AM Mitzey… - Melanoma …, 2010 - journals.lww.com
Canine malignant melanoma (CMM) resembles human malignant melanoma in terms of
metastatic behavior, refractoriness to standard therapy, and tumor antigen expression but it is …
metastatic behavior, refractoriness to standard therapy, and tumor antigen expression but it is …