Since the 1920s, it has been known that the repetitive brain trauma associated with boxing
may produce a progressive neurological deterioration, originally termed dementia pugilistica, …

Chronic traumatic encephalopathy is a progressive tauopathy that occurs as a consequence
of repetitive mild traumatic brain injury. We analysed post-mortem brains obtained from a …

Chronic traumatic encephalopathy (CTE) has been linked to participation in contact sports
such as boxing and American football. CTE results in a progressive decline of memory and …

It has been understood for decades that certain sporting activities may increase an athlete’s
risk of developing a neurodegenerative disease later in life. Not surprisingly, this association …

Chronic traumatic encephalopathy (CTE) is a neurodegeneration characterized by the
abnormal accumulation of hyperphosphorylated tau protein within the brain. Like many other …

Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms,
and long-term cognitive disability. We examined a case series of postmortem brains from US …

Epidemiological evidence suggests that the incidence of amyotrophic lateral sclerosis is
increased in association with head injury. Repetitive head injury is also associated with the …

Importance Players of American football may be at increased risk of long-term neurological
conditions, particularly chronic traumatic encephalopathy (CTE). Objective To determine the …

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

Clinicopathologic correlation studies are critically important for the field of Alzheimer disease
(AD) research. Studies on human subjects with autopsy confirmation entail numerous …