Epilepsy is a common neurological disorder characterized by recurrent seizures. These
seizures are due to abnormal excessive and synchronous neuronal activity in the brain caused …

TDP‐43 is the major component of pathological inclusions in most ALS patients and in up to
50% of patients with frontotemporal dementia (FTD). Heterozygous missense mutations in …

A hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause
of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How this mutation …

Energy metabolism has been repeatedly linked to amyotrophic lateral sclerosis (ALS). Yet,
motor neuron (MN) metabolism remains poorly studied and it is unknown if ALS MNs differ …

Introduction Tauopathies are neurodegenerative diseases characterized by TAU protein–related
pathology, including frontotemporal dementia and Alzheimer's disease among others. …

Background Quantitative real-time PCR (qPCR) is a commonly used technique to quantify
gene expression levels. Validated normalization is essential to obtain reliable qPCR data. In …

Objective Febrile seizures ( FS ) are fever‐associated convulsions, being the most common
seizure disorder in early childhood. A subgroup of these children later develops epilepsy …

Febrile seizures (FS) are the most common type of seizures in childhood and are suggested
to play a role in the development of temporal lobe epilepsy (TLE). Animal studies …

Prolonged febrile seizures (FS) are a risk factor for the development of hippocampal‐associated
temporal lobe epilepsy. The dentate gyrus is the major gateway to the hippocampal …

Purpose: Febrile seizures (FS), the most frequent seizure type during childhood, have been
linked to temporal lobe epilepsy (TLE) in adulthood. Yet, underlying mechanisms are still …