To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …

Background: Because the projected increase in the number of diabetic patients is expected
to strain the capabilities of health care providers worldwide, we are challenged to find ways …

Highlights • Most research on the microbiota–gut brain axis has been conducted on animals.
• We reviewed recent human studies on gut microbiota and mental health. • Small sample …

Background & Aims It is unclear whether the identification of individuals at risk of cirrhosis
using non-invasive tests can be improved by repeated measurements. Herein, we tested …

Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

Background Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder,
affecting more than 10% of the general population worldwide. Although a genetic component …

Background & Aims Noninvasive scoring systems are used to identify persons with advanced
liver fibrosis. We investigated the ability of scoring systems to identify individuals in the …

Objective IBS shows genetic predisposition, but adequately powered gene-hunting efforts
have been scarce so far. We sought to identify true IBS genetic risk factors by means of …

Impaired appetite and weight changes are commonly seen in patients with depression, but
the pathophysiology behind this imbalance between energy intake and energy expenditure …

Gut mucosal microbes evolved closest to the host, developing specialized local communities.
There is, however, insufficient knowledge of these communities as most studies have …