Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

PR Gonzales, MW Pesesky, R Bouley, A Ballard… - Nature chemical …, 2015 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent multidrug-resistant
pathogens worldwide, exhibiting increasing resistance to the latest antibiotic …

Staphylococcus aureus infects osteoclasts and replicates intracellularly

JL Krauss, PM Roper, A Ballard, CC Shih… - MBio, 2019 - Am Soc Microbiol
Osteomyelitis (OM), or inflammation of bone tissue, occurs most frequently as a result of
bacterial infection and severely perturbs bone structure. OM is predominantly caused by …

[HTML][HTML] The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca2+–NFATc1 axis

A Ballard, R Zeng, A Zarei, C Shao, L Cox… - Journal of Biological …, 2020 - ASBMB
Dynamic regulation of the mitochondrial network by mitofusins (MFNs) modulates energy
production, cell survival, and many intracellular signaling events, including calcium handling. …

Pro-453 to Ser mutation in CYP21 is associated with nonclassic steroid 21-hydroxylase deficiency.

D Owerbach, L Sherman, AL Ballard… - Molecular …, 1992 - academic.oup.com
Steroid 21-hydroxylase deficiency is the leading cause of impaired cortisol synthesis in
congenital adrenal hyperplasia (CAH), with the nonclassic form (NC) comprising approximately 1…

Nucleotide sequences of normal and rearranged RNA segments 10 of human rotaviruses

A Ballard, MA McCrae… - Journal of general …, 1992 - microbiologyresearch.org
Normal and rearranged RNA segments 10 of group A rotaviruses isolated from a chronically
infected immunodeficient child were amplified by the polymerase chain reaction as full-…

Respiratory nitrate reductase from Paracoccus denitrificans Evidence for two b‐type haems in the γ subunit and properties of a water‐soluble active enzyme …

AL Ballard, SJ Ferguson - European journal of biochemistry, 1988 - Wiley Online Library
1 The b‐type haem centres of the three (α, β and γ) subunit nitrate reductase from
Paracoccus denitrificans have been analysed by redox potentiometry. Two components were …

Salt-wasting congenital adrenal hyperplasia: detection and characterization of mutations in the steroid 21-hydroxylase gene, CYP21, using the polymerase chain …

D Owerbach, AL Ballard… - The Journal of Clinical …, 1992 - academic.oup.com
We have characterized mutations in the steroid 21-hydroxylase gene (CYP21) in salt-wasting
congenital adrenal hyperplasia (SW-CAH) subjects, healthy control subjects, and affected …

Manipulation of the Alternative NF κB Pathway in Mice Has Sexually Dimorphic Effects on Bone

…, C Yang, J Gibbs, JL Davis, A Ballard… - Journal of Bone and …, 2019 - academic.oup.com
Alternative NF κB signaling promotes osteoclastogenesis and pathological bone loss, but
the effect of sex on phenotype has not been explored. We disrupted alternative NF κB …

Membrane dynamics at the nuclear exchange junction during early mating (one to four hours) in the ciliate Tetrahymena thermophila

…, J Orias, E Hamilton, S Guerrier, A Ballard… - Eukaryotic …, 2015 - Am Soc Microbiol
Using serial-section transmission electron microscopy and three-dimensional (3D) electron
tomography, we characterized membrane dynamics that accompany the construction of a …

Osteolineage depletion of mitofusin2 enhances cortical bone formation in female mice

A Zarei, A Ballard, L Cox, P Bayguinov, T Harris… - Bone, 2021 - Elsevier
Mitochondria are essential organelles that form highly complex, interconnected dynamic
networks inside cells. The GTPase mitofusin 2 (MFN2) is a highly conserved outer …