[HTML][HTML] A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA
Cell-free DNA (cfDNA) has the potential to inform tumor subtype classification and help guide
clinical precision oncology. Here we develop Griffin, a framework for profiling nucleosome …
clinical precision oncology. Here we develop Griffin, a framework for profiling nucleosome …
CDK12-Mutated Prostate Cancer: Clinical Outcomes With Standard Therapies and Immune Checkpoint Blockade
…, LC Brown, RR McKay, T Dorff, ACH Hoge… - JCO precision …, 2020 - ascopubs.org
PURPOSE Translational studies have shown that CDK12 mutations may delineate an
immunoresponsive subgroup of prostate cancer, characterized by high neo-antigen burden. Given …
immunoresponsive subgroup of prostate cancer, characterized by high neo-antigen burden. Given …
[HTML][HTML] DNA-based copy number analysis confirms genomic evolution of PDX models
ACH Hoge, M Getz, A Zimmer, M Ko, L Raz… - NPJ Precision …, 2022 - nature.com
Genomic evolution of patient-derived xenografts (PDXs) may lead to their gradual divergence
away of their tumors of origin. We previously reported the genomic evolution of the copy …
away of their tumors of origin. We previously reported the genomic evolution of the copy …
[HTML][HTML] Patterns of structural variation define prostate cancer across disease states
The complex genomic landscape of prostate cancer evolves across disease states under
therapeutic pressure directed toward inhibiting androgen receptor (AR) signaling. While …
therapeutic pressure directed toward inhibiting androgen receptor (AR) signaling. While …
[HTML][HTML] Non-responder phenotype reveals apparent microbiome-wide antibiotic tolerance in the murine gut
C Diener, ACH Hoge, SM Kearney… - Communications …, 2021 - nature.com
Broad spectrum antibiotics cause both transient and lasting damage to the ecology of the
gut microbiome. Antibiotic-induced loss of gut bacterial diversity has been linked to …
gut microbiome. Antibiotic-induced loss of gut bacterial diversity has been linked to …
Publisher Correction: DNA-based copy number analysis confirms genomic evolution of PDX models
ACH Hoge, M Getz, A Zimmer, M Ko, L Raz… - NPJ Precision …, 2022 - ncbi.nlm.nih.gov
… Anna CH Hoge, # 1 Michal Getz, # 2 Anat Zimmer, 1 Minjeong Ko, 1 Linoy Raz, 2
Rameen Beroukhim, 3, 4, 5 Todd R. Golub, 3, 4, 5 Gavin Ha, corresponding author 1 and …
Rameen Beroukhim, 3, 4, 5 Todd R. Golub, 3, 4, 5 Gavin Ha, corresponding author 1 and …
Non-responder phenotype reveals microbiome-wide antibiotic resistance in the murine gut
C Diener, ACH Hoge, SM Kearney, SE Erdman… - bioRxiv, 2019 - biorxiv.org
Broad spectrum antibiotics can cause both transient and lasting damage to the ecology of
the gut microbiome. Loss of gut bacterial diversity has been linked to immune dysregulation …
the gut microbiome. Loss of gut bacterial diversity has been linked to immune dysregulation …
Author Correction: A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA
…, N De Sarkar, KA Collier, ACH Hoge… - nature …, 2023 - ncbi.nlm.nih.gov
… Anna-Lisa Doebley, 1, 2, 3 Minjeong Ko, 1 Hanna Liao, 2, 4 A. Eden Cruikshank, 1, 2
Katheryn Santos, 5 Caroline Kikawa, 3 Joseph B. Hiatt, 1, 6 Robert D. … Collier, 7 Anna CH …
Katheryn Santos, 5 Caroline Kikawa, 3 Joseph B. Hiatt, 1, 6 Robert D. … Collier, 7 Anna CH …
Somatic mutation but not aneuploidy differentiates lung cancer in never-smokers and smokers
S Moorthi, A Paguirigan, M Ko, M Pettinger, ACH Hoge… - bioRxiv, 2023 - biorxiv.org
Lung cancer in never-smokers disproportionately affects older women. To understand the
mutational landscape of this cohort, we performed detailed genome characterization of 73 …
mutational landscape of this cohort, we performed detailed genome characterization of 73 …
[HTML][HTML] CAMELS-CH: hydro-meteorological time series and landscape attributes for 331 catchments in hydrologic Switzerland
M Höge, M Kauzlaric, R Siber… - Earth System …, 2023 - essd.copernicus.org
We present CAMELS-CH (Catchment Attributes and MEteorology for large-sample Studies -
Switzerland), a large-sample hydro-meteorological data set for hydrological Switzerland in …
Switzerland), a large-sample hydro-meteorological data set for hydrological Switzerland in …