Protein kinase M-ζ (PKM-ζ) is a constitutively active form of atypical protein kinase C that is
exclusively expressed in the brain and implicated in the maintenance of long-term memory 1 , …

To clarify the role of arsenic in human carcinogenesis, the mortality experience of 8,047
white male smelter workers exposed to arsenic trioxide during 1938–63 was studied and …

BACKGROUND: CYP2B6 is the primary enzyme involved in bupropion (Zyban; GlaxoSmithKline,
Research Triangle Park, North Carolina) metabolism. Genetic polymorphisms in …

Although drugs of abuse have different chemical structures and interact with different protein
targets, all appear to usurp common neuronal systems that regulate reward and motivation. …

Background The level of evidence for HIV transmission risk through condomless sex in
serodifferent gay couples with the HIV-positive partner taking virally suppressive antiretroviral …

The replication of human immunodeficiency virus type 1 (HIV-1) in nondividing host cells
such as those of macrophage lineage is an important feature of AIDS pathogenesis. The …

Background A 2017 meta-analysis of data from 25 randomised controlled trials (RCTs) of
vitamin D supplementation for the prevention of acute respiratory infections (ARIs) revealed a …

Background Tens of millions of children are exposed to Mycobacterium tuberculosis
globally every year; however, there are no contemporary estimates of the risk of developing …

Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …

The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …