CD4 Th cells producing the proinflammatory cytokine IL-17 (Th17) have been implicated in
a number of inflammatory arthritides including the spondyloarthritides. Th17 development is …

RATIONALE In recent years, research and applications of the N 2 O site‐specific nitrogen
isotope composition have advanced, reflecting awareness of the contribution of N 2 O to the …

The human leukocyte Ag HLA-B27 (B27) is strongly associated with the spondyloarthritides.
B27 can be expressed at the cell surface of APC as both classical β 2-microglobulin–…

This chapter considers the practice of liming-what information is required and hence what
measurements should be made to answer the questions, is a soil acid, is lime required, and, if …

Objective Human leucocyte antigen (HLA)-B27 and endoplasmic reticulum aminopeptidase
1 (ERAP1) are strongly associated with ankylosing spondylitis (AS). ERAP1 is a key …

Regulatory T cells (Tregs) play an important role in controlling inflammation and limiting
autoimmunity, but their phenotypes at inflammatory sites in human disease are poorly …

Possession of HLA-B27 (B27) strongly predisposes to the development of spondyloarthritis.
B27 forms classical heterotrimeric complexes with β 2-microglobulin (β2m) and peptide and (…

Objective Spondylarthritides (SpA), including ankylosing spondylitis (AS), are common
inflammatory rheumatic diseases that are strongly associated with positivity for the HLA class I …

Objective In the spondyloarthritides (SpA), increased numbers of CD4+ T cells express killer
cell immunoglobulin‐like receptor 3DL2 (KIR‐3DL2). The aim of this study was to determine …

Objectives To explore the functional basis for the association between ankylosing spondylitis
(AS) and single-nucleotide polymorphisms (SNPs) in the IL23R-IL12RB2 intergenic region. …