The Global Enteric Multicenter Study (GEMS) demonstrated that Shigella and enterotoxigenic
Escherichia coli (ETEC) producing heat stable toxin (ST) (either alone or in combination …

Background Rotavirus is a leading cause of diarrhoeal mortality in children but there is
considerable disagreement about how many deaths occur each year. Methods and findings We …

Background The association between childhood diarrheal disease and linear growth
faltering in developing countries is well described. However, the impact attributed to specific …

Background Pediatric diarrhea can be caused by a wide variety of pathogens, from bacteria
to viruses to protozoa. Pathogen prevalence is often described as seasonal, peaking …

Background Stunting affects >20% of children <5 years old worldwide and disproportionately
impacts underserved communities. The Vaccine Impact on Diarrhea in Africa (VIDA) Study …

Background We evaluated the burden of Shigella spp from children aged 0–59 months with
medically attended moderate-to-severe diarrhea and matched controls at sites in Mali, The …

Background Despite antibiotic prescription being recommended for dysentery and suspected
cholera only, diarrhea still triggers unwarranted antibiotic prescription. We evaluated …

Background As part of the Vaccine Impact on Diarrhea in Africa (VIDA) Study, we examined
the prevalence, clinical presentation, and seasonality of Cryptosporidium in children to …

Background Pediatric exposures to unsafe sources of water, unsafely managed sanitation,
and animals are prevalent in low- and middle-income countries. In the Vaccine Impact on …

Background Diarrheal disease is heterogeneous, including watery diarrhea (WD) and
dysentery, some cases of which become persistent diarrhea (PD). Changes in risk over time …