User profiles for Anna Vangone
 | Anna VangoneLarge Molecule Research - Roche Verified email at uu.nl Cited by 3123 |
PRODIGY: a web server for predicting the binding affinity of protein–protein complexes
Gaining insights into the structural determinants of protein–protein interactions holds the
key for a deeper understanding of biological functions, diseases and development of …
key for a deeper understanding of biological functions, diseases and development of …
Contacts-based prediction of binding affinity in protein–protein complexes
A Vangone, AMJJ Bonvin - elife, 2015 - elifesciences.org
10.7554/eLife.07454.001 Almost all critical functions in cells rely on specific protein–protein
interactions. Understanding these is therefore crucial in the investigation of biological …
interactions. Understanding these is therefore crucial in the investigation of biological …
Updates to the integrated protein–protein interaction benchmarks: docking benchmark version 5 and affinity benchmark version 2
We present an updated and integrated version of our widely used protein–protein docking
and binding affinity benchmarks. The benchmarks consist of non-redundant, high-quality …
and binding affinity benchmarks. The benchmarks consist of non-redundant, high-quality …
COCOMAPS: a web application to analyze and visualize contacts at the interface of biomolecular complexes
Herein we present COCOMAPS, a novel tool for analyzing, visualizing and comparing the
interface in protein–protein and protein–nucleic acids complexes. COCOMAPS combines …
interface in protein–protein and protein–nucleic acids complexes. COCOMAPS combines …
Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: a CASP‐CAPRI experiment
We present the results for CAPRI Round 30, the first joint CASP‐CAPRI experiment, which
brought together experts from the protein structure prediction and protein–protein docking …
brought together experts from the protein structure prediction and protein–protein docking …
Large-scale prediction of binding affinity in protein–small ligand complexes: The PRODIGY-LIG web server
Recently we published PROtein binDIng enerGY (PRODIGY), a web-server for the prediction
of binding affinity in protein–protein complexes. By using a combination of simple structural …
of binding affinity in protein–protein complexes. By using a combination of simple structural …
[HTML][HTML] Performance of HADDOCK and a simple contact-based protein–ligand binding affinity predictor in the D3R Grand Challenge 2
We present the performance of HADDOCK, our information-driven docking software, in the
second edition of the D3R Grand Challenge. In this blind experiment, participants were …
second edition of the D3R Grand Challenge. In this blind experiment, participants were …
iSEE: Interface structure, evolution, and energy‐based machine learning predictor of binding affinity changes upon mutations
Quantitative evaluation of binding affinity changes upon mutations is crucial for protein
engineering and drug design. Machine learning‐based methods are gaining increasing …
engineering and drug design. Machine learning‐based methods are gaining increasing …
PRODIGY: a contact-based predictor of binding affinity in protein-protein complexes
A Vangone, AMJJ Bonvin - Bio-protocol, 2017 - bio-protocol.org
Biomolecular interactions between proteins regulate and control almost every biological
process in the cell. Understanding these interactions is therefore a crucial step in the …
process in the cell. Understanding these interactions is therefore a crucial step in the …
[HTML][HTML] D936Y and other mutations in the fusion core of the SARS-CoV-2 spike protein heptad repeat 1: frequency, geographical distribution, and structural effect
The crown of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is constituted
by its spike (S) glycoprotein. S protein mediates the SARS-CoV-2 entry into the host cells…
by its spike (S) glycoprotein. S protein mediates the SARS-CoV-2 entry into the host cells…