User profiles for Anna Yakovleva

Anna Yakovleva

University of Oxford
Verified email at some.ox.ac.uk
Cited by 3592

[PDF][PDF] Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity

…, M Hosmillo, ML Pinckert, I Georgana, A Yakovleva… - Cell, 2021 - cell.com
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …

[HTML][HTML] Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

…, SL Caddy, FA Khokhar, A Yakovleva… - The Lancet infectious …, 2020 - thelancet.com
Background The burden and influence of health-care associated severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …

[HTML][HTML] The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens

…, M Bortolomeazzi, SK Venkata, A Tourna, A Yakovleva… - Genome biology, 2019 - Springer
The Network of Cancer Genes (NCG) is a manually curated repository of 2372 genes whose
somatic modifications have known or predicted cancer driver roles. These genes were …

Patterns of within-host genetic diversity in SARS-CoV-2

…, M Hosmillo, ML Pinckert, I Georgana, A Yakovleva… - elife, 2021 - elifesciences.org
Monitoring the spread of SARS-CoV-2 and reconstructing transmission chains has become
a major public health focus for many governments around the world. The modest mutation …

[HTML][HTML] Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

…, WM Zelek, A Smielewska, A Yakovleva… - Nature …, 2020 - nature.com
The response to the coronavirus disease 2019 (COVID-19) pandemic has been hampered
by lack of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Inhibition of polyamine biosynthesis is a broad-spectrum strategy against RNA viruses

…, G Moratorio, PJ Hooikaas, A Yakovleva… - Journal of …, 2016 - Am Soc Microbiol
RNA viruses present an extraordinary threat to human health, given their sudden and
unpredictable appearance, the potential for rapid spread among the human population, and their …

[HTML][HTML] Tracking SARS-COV-2 variants using Nanopore sequencing in Ukraine in 2021

A Yakovleva, G Kovalenko, M Redlinger… - Scientific reports, 2022 - nature.com
The use of real-time genomic epidemiology has enabled the tracking of the global spread of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), informing evidence-based …

Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections

…, AS Jahun, LG Caller, SL Caddy, A Yakovleva… - elife, 2021 - elifesciences.org
SARS-CoV-2 is notable both for its rapid spread, and for the heterogeneity of its patterns of
transmission, with multiple published incidences of superspreading behaviour. Here, we …

[HTML][HTML] Advances in the Diagnosis of Human Opisthorchiasis: Development of Opisthorchis viverrini Antigen Detection in Urine

C Worasith, C Kamamia, A Yakovleva… - PLoS neglected …, 2015 - journals.plos.org
Background Many strategies to control opisthorchiasis have been employed in Thailand,
but not in the other neighbouring countries. Specific control methods include mass drug …

Single-molecule long-read 16S sequencing to characterize the lung microbiome from mechanically ventilated patients with suspected pneumonia

I Toma, MO Siegel, J Keiser, A Yakovleva… - Journal of clinical …, 2014 - Am Soc Microbiol
In critically ill patients, the development of pneumonia results in significant morbidity and
mortality and additional health care costs. The accurate and rapid identification of the microbial …