The exon junction complex (EJC) is a key regulator of posttranscriptional mRNA fate and
binds to mRNA during splicing. Although the composition of EJCs is well understood, the …

Loss of RNA homeostasis underlies numerous neurodegenerative and neuroinflammatory
diseases. However, the molecular mechanisms that trigger neuroinflammation are poorly …

The export of messenger RNAs (mRNAs) is the final of several nuclear posttranscriptional
steps of gene expression. The formation of export-competent mRNPs involves the recruitment …

Folded RNA elements that block processive 5′ → 3′ cellular exoribonucleases (xrRNAs)
to produce biologically active viral noncoding RNAs have been discovered in flaviviruses, …

Productive splicing of human precursor messenger RNAs (pre-mRNAs) requires the correct
selection of authentic splice sites (SS) from the large pool of potential SS. Although SS …

During the decoding of a subset of mRNAs, a proportion of ribosomes productively shift to
the− 1 reading frame at specific slippage-prone sites in a phenomenon known as programmed…

During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus
RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by …

Many viruses produce protein-coding and noncoding subgenomic RNAs (sgRNAs) that are
critical for infection. A recently discovered pathway for viral sgRNA production uses …

NKAP is a highly conserved protein with roles in transcriptional repression, T-cell development,
maturation and acquisition of functional competency and maintenance and survival of …

Exoribonuclease-resistant RNAs (xrRNAs) are discrete elements that block the progression
of 5′ to 3′ exoribonucleases using specifically folded RNA structures. A recently …