The migration of many cell types relies on the formation of actomyosin-dependent protrusions
called blebs, but the mechanisms responsible for focusing this kind of protrusive activity to …

In Multiple Sclerosis (MS) the relationship between disease process in normal-appearing
white matter (NAWM) and the development of white matter lesions is not well understood. In …

Similar to many other organisms, zebrafish primordial germ cells (PGCs) are specified at a
location distinct from that of gonadal somatic cells. Guided by chemotactic cues, PGCs …

Introduction: Magnetic Resonance Imaging is a sensitive technique for detecting white matter
(WM) MS lesions, but the relation with clinical disability is low. Because of this, changes in …

To study the mechanisms controlling front-rear polarity in migrating cells, we used zebrafish
primordial germ cells (PGCs) as an in vivo model. We find that polarity of bleb-driven …

Background: Borrelia infections, especially chronic neuroborreliosis (NB), may cause
considerable diagnostic problems. This diagnosis is based on symptoms and findings in the …

Epithelial morphogenesis generates the shape of the tooth crown. This is driven by
patterned differentiation of cells into enamel knots, root-forming cervical loops and enamel-forming …

Blebs are cell protrusions generated by local membrane–cortex detachments followed by
expansion of the plasma membrane. Blebs are formed by some migrating cells, eg primordial …

Blebs are cell protrusions generated by local membrane-cortex detachments followed by
expansion of the plasma membrane. Blebs are formed by some migrating cells, for example …

Background: The multiple sclerosis (MS) severity scale (MSSS) is a new scoring procedure
to clinically characterize the rate of disease progression in MS, rather than the disability of …