Several vertebrate microRNAs (miRNAs) have been implicated in cellular processes such as
muscle differentiation, synapse function, and insulin secretion. In addition, analysis of Dicer …

Background Aberrant regulation of cell migration drives progression of many diseases,
including cancer cell invasion and metastasis formation. Analysis of tumour invasion and …

Macrophages are key cellular contributors to the pathogenesis of COVID-19, the disease
caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on a …

Mural cells of the vertebrate brain maintain vascular integrity and function, play roles in stroke
and are involved in maintenance of neural stem cells. However, the origins, diversity and …

Angiogenesis is responsible for tissue vascularization during development, as well as in
pathological contexts, including cancer and ischemia. Vascular endothelial growth factors (…

Epithelia must eliminate apoptotic cells to preserve tissue barriers and prevent inflammation.
Several different mechanisms exist for apoptotic clearance, including efferocytosis 2 , 3 and …

The lymphatic vasculature plays roles in tissue fluid balance, immune cell trafficking, fatty
acid absorption, cancer metastasis, and cardiovascular disease. Lymphatic vessels form by …

Atrial natriuretic peptide (nppa/anf) and brain natriuretic peptide (nppb/bnp) form a gene cluster
with expression in the chambers of the developing heart. Despite restricted expression, a …

Mural cells (MCs) are essential for blood vessel stability and function; however, the
mechanisms that regulate MC development remain incompletely understood, in particular those …

Angiogenesis and vascular remodeling are driven by extensive endothelial cell movements.
Here, we present in vivo evidence that endothelial cell movements are associated with …