Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B
…, E Rappaport, S Kawauchi, AD Lander, AL Calof… - Nature …, 2004 - nature.com
Cornelia de Lange syndrome (CdLS; OMIM 122470) is a dominantly inherited multisystem
developmental disorder characterized by growth and cognitive retardation; abnormalities of …
developmental disorder characterized by growth and cognitive retardation; abnormalities of …
Analysis of neurogenesis in a mammalian neuroepithelium: proliferation and differentiation of an olfactory neuron precursor in vitro
AL Calof, DM Chikaraishi - Neuron, 1989 - Elsevier
Abstract Development of a culture system for mammalian olfactory epithelium has permitted
the process of neurogenesis to be examined in vitro. Antibody markers allowing the …
the process of neurogenesis to be examined in vitro. Antibody markers allowing the …
[HTML][HTML] Cell lineages and the logic of proliferative control
It is widely accepted that the growth and regeneration of tissues and organs is tightly
controlled. Although experimental studies are beginning to reveal molecular mechanisms …
controlled. Although experimental studies are beginning to reveal molecular mechanisms …
GDF11 controls the timing of progenitor cell competence in developing retina
…, HH Wu, AD Lander, KM Lyons, MM Matzuk, AL Calof - Science, 2005 - science.org
The orderly generation of cell types in the developing retina is thought to be regulated by
changes in the competence of multipotent progenitors. Here, we show that a secreted factor, …
changes in the competence of multipotent progenitors. Here, we show that a secreted factor, …
[HTML][HTML] Autoregulation of neurogenesis by GDF11
…, S Jaramillo, KM Lyons, JE Johnson, AL Calof - Neuron, 2003 - cell.com
In the olfactory epithelium (OE), generation of new neurons by neuronal progenitors is
inhibited by a signal from neurons themselves. Here we provide evidence that this feedback …
inhibited by a signal from neurons themselves. Here we provide evidence that this feedback …
Identification and molecular regulation of neural stem cells in the olfactory epithelium
CL Beites, S Kawauchi, CE Crocker, AL Calof - Experimental cell research, 2005 - Elsevier
The sensory neurons that subserve olfaction, olfactory receptor neurons (ORNs), are
regenerated throughout life, making the neuroepithelium in which they reside [the olfactory …
regenerated throughout life, making the neuroepithelium in which they reside [the olfactory …
[HTML][HTML] Multiple Organ System Defects and Transcriptional Dysregulation in the Nipbl+/− Mouse, a Model of Cornelia de Lange Syndrome
S Kawauchi, AL Calof, R Santos, ME Lopez-Burks… - PLoS …, 2009 - journals.plos.org
Cornelia de Lange Syndrome (CdLS) is a multi-organ system birth defects disorder linked,
in at least half of cases, to heterozygous mutations in the NIPBL gene. In animals and fungi, …
in at least half of cases, to heterozygous mutations in the NIPBL gene. In animals and fungi, …
[HTML][HTML] What does the concept of the stem cell niche really mean today?
…, E Fuchs, D Montarras, M Buckingham, AL Calof… - BMC biology, 2012 - Springer
© 2012 Lander et al; licensee BioMed Central Ltd. This is an Open Access article distributed
under the terms of the Creative Commons Attribution License (http://creativecommons. org/…
under the terms of the Creative Commons Attribution License (http://creativecommons. org/…
Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse
…, JM Hébert, SK McConnell, I Mason, AL Calof - 2005 - journals.biologists.com
In vertebrate olfactory epithelium (OE), neurogenesis proceeds continuously, suggesting
that endogenous signals support survival and proliferation of stem and progenitor cells. We …
that endogenous signals support survival and proliferation of stem and progenitor cells. We …
BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor
J Shou, PC Rim, AL Calof - Nature neuroscience, 1999 - nature.com
Bone morphogenetic proteins (BMPs), negative regulators of neural determination in the
early embryo, were found to be potent inhibitors of neurogenesis in olfactory epithelium (OE) …
early embryo, were found to be potent inhibitors of neurogenesis in olfactory epithelium (OE) …