Several lines of evidence suggest a major role of the trigeminovascular system in the
pathogenesis of migraine. Using functional magnetic resonance imaging (fMRI), we compared …

Objective: Migraine patients have dysfunctional cortical olfactory processing and very often
report hypersensitivity and phobic symptoms to odors during acute headache attacks. …

It is generally accepted that acute painful experience is influenced by context information
shaping expectation and modulating attention, arousal, stress, and mood. However, little is …

Chronic pain is characterised by an ongoing and fluctuating intensity over time. Here, we
investigated how the trajectory of the patients' endogenous pain is encoded in the brain. In …

The thalamus contains third-order relay neurons of the trigeminal system, and animal
models as well as preliminary imaging studies in small cohorts of migraine patients have …

Background Several previous studies have investigated cortical abnormalities, specifically
cortical thickness, in patients with migraine, with variable results. The relatively small sample …

Migraine is a complex neurological disorder affecting approximately 12% of the population.
The pathophysiology is not yet fully understood, however the clinical features of the disease, …

Although humans are generally capable of distinguishing single events of pain or touch,
recent research suggested that both modalities activate a network of similar brain regions. By …

Habituation deficits in various sensory modalities have been observed in migraine patients
in several experimental designs. The underlying neuronal mechanisms are, however, still …

The cerebral cortex, brainstem and trigemino-vascular system are considered the main
neuronal structures involved in the pathogenesis of migraine. Recent discoveries regarding …