User profiles for Anne-Marie Gerdes
 | Anne-Marie GerdesProfessor of Clinical Genetics, University of Copenhagen Verified email at regionh.dk Cited by 18646 |
Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers
Importance The clinical management ofBRCA1andBRCA2mutation carriers requires accurate,
prospective cancer risk estimates. Objectives To estimate age-specific risks of breast, …
prospective cancer risk estimates. Objectives To estimate age-specific risks of breast, …
[HTML][HTML] Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial
Background Observational studies report reduced colorectal cancer in regular aspirin
consumers. Randomised controlled trials have shown reduced risk of adenomas but none have …
consumers. Randomised controlled trials have shown reduced risk of adenomas but none have …
Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 …
…, L Senter, K Sweet, M Thomassen, AM Gerdes… - … Biomarkers & Prevention, 2012 - AACR
Background: Previously, small studies have found that BRCA1 and BRCA2 breast tumors
differ in their pathology. Analysis of larger datasets of mutation carriers should allow further …
differ in their pathology. Analysis of larger datasets of mutation carriers should allow further …
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer
…, SL Neuhausen, YC Ding, B Ejlertsen, AM Gerdes… - Jama, 2015 - jamanetwork.com
Importance Limited information about the relationship between specific mutations
inBRCA1orBRCA2(BRCA1/2) and cancer risk exists. Objective To identify mutation-specific cancer …
inBRCA1orBRCA2(BRCA1/2) and cancer risk exists. Objective To identify mutation-specific cancer …
Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium 'care for CMMRD'(C4CMMRD)
…, O Caron, C Colas, N Entz-Werle, AM Gerdes… - Journal of medical …, 2014 - jmg.bmj.com
Constitutional mismatch repair deficiency (CMMRD) syndrome is a distinct childhood cancer
predisposition syndrome that results from biallelic germline mutations in one of the four …
predisposition syndrome that results from biallelic germline mutations in one of the four …
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general …
…, K Harbst, J Rantala, H Ehrencrona, AM Gerdes… - Nature …, 2010 - nature.com
Germline BRCA1 mutations predispose to breast cancer. To identify genetic modifiers of this
risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 …
risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 …
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
…, A Gentry-Maharaj, AM Gerdes… - Nature …, 2017 - nature.com
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC),
we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …
we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …
Identification of six new susceptibility loci for invasive epithelial ovarian cancer
…, YC Ding, TVO Hansen, L Jønson, AM Gerdes… - Nature …, 2015 - nature.com
Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC)
susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and …
susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and …
[PDF][PDF] Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
…, IL Andrulis, H Ozcelik, AM Gerdes… - The American Journal of …, 2008 - cell.com
Germline mutations in BRCA1 and BRCA2 confer high risks of breast cancer. However,
evidence suggests that these risks are modified by other genetic or environmental factors that …
evidence suggests that these risks are modified by other genetic or environmental factors that …
[HTML][HTML] Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a …
Background Lynch syndrome is associated with an increased risk of colorectal cancer and
with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group …
with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group …