Burst firing is commonly observed in many sensory systems and is proposed to transmit
information reliably. Although a number of biophysical burst mechanisms have been identified, …

We investigated the development of L2/3 pyramidal cell (PC) circuitry in juvenile mice from
postnatal day 10 (P10) to P29. Using whole cell recordings in an in vitro thalamocortical slice …

The lateral parabrachial nucleus (lPBN) is a major target of spinal projection neurons
conveying nociceptive input into supraspinal structures. However, the functional role of distinct …

Short interspike intervals such as those that occur during burst firing are hypothesized to be
distinct features of the neural code. Although a number of correlations between the …

The interplay between inhibition and excitation is at the core of cortical network activity. In
many cortices, including auditory cortex (ACx), interactions between excitatory and inhibitory …

In vivo voltage clamp recordings have provided new insights into the synaptic mechanisms
that underlie processing in the primary auditory cortex. Of particular importance are the …

The time course of inhibition plays an important role in cortical sensitivity, tuning, and temporal
response properties. We investigated the development of L2/3 inhibitory circuitry between …

Throughout the brain, the recruitment of feedforward and recurrent inhibition shapes neural
responses. However, disentangling the relative contributions of these often-overlapping …

Stimulus properties, attention, and behavioral context influence correlations between the
spike times produced by a pair of neurons. However, the biophysical mechanisms that …

Inhibitory microcircuits play an essential role in regulating cortical responses to sensory
stimuli. Interneurons that inhibit dendritic or somatic integration act as gatekeepers for neural …