A mechanism for reorientation of cortical microtubule arrays driven by microtubule severing

JJ Lindeboom, M Nakamura, A Hibbel, K Shundyak… - Science, 2013 - science.org
Introduction Organization of the cortical cytoskeleton guides the growth and morphogenesis
of organisms, from bacteria to higher plants, that depend on cell walls. By positioning wall-…

Regulation of microtubule growth and catastrophe: unifying theory and experiment

H Bowne-Anderson, A Hibbel, J Howard - Trends in cell biology, 2015 - cell.com
Recent studies have found that microtubule-associated proteins (MAPs) can regulate the
dynamical properties of microtubules in unexpected ways. For most MAPs, there is an inverse …

Challenging the cholinergic system in mild cognitive impairment: a pharmacological fMRI study

R Goekoop, SARB Rombouts, C Jonker, A Hibbel… - Neuroimage, 2004 - Elsevier
Mild cognitive impairment (MCI) often represents an early form of Alzheimer disease (AD).
In both MCI and AD, characteristic cholinergic changes may occur. Functional magnetic …

Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

A Hibbel, A Bogdanova, M Mahamdeh, A Jannasch… - Elife, 2015 - elifesciences.org
10.7554/eLife.10542.001 The size and position of mitotic spindles is determined by the lengths
of their constituent microtubules. Regulation of microtubule length requires feedback to …

CLASP stabilization of plus ends created by severing promotes microtubule creation and reorientation

JJ Lindeboom, M Nakamura, M Saltini, A Hibbel… - Journal of Cell …, 2019 - rupress.org
Central to the building and reorganizing cytoskeletal arrays is creation of new polymers.
Although nucleation has been the major focus of study for microtubule generation, severing has …

CLASP promotes microtubule array reorientation by acting as a specific severing rescue factor

JJ Lindeboom, M Nakamura, M Saltini, A Hibbel… - BioRxiv, 2017 - biorxiv.org
Eukaryotic cells build microtubule arrays to perform essential cellular functions, including
division and morphogenesis. Central to building and reorganizing these cytoskeletal arrays is …

[PDF][PDF] CLASP stabilizes microtubule plus ends created by serving to drive cortical array reorientation

JJ Lindeboom, M Nakamura, M Saltini, A Hibbel… - J Cell Biol, 2018 - ir.amolf.nl
Central to building and reorganizing cytoskeletal arrays is the creation of new polymers.
While nucleation has been the major focus of study for new microtubule generation, severing …

[PDF][PDF] CLASP stabilizes microtubule plus ends after severing to facilitate light-induced microtubule reorientation

JJ Lindeboom, M Nakamura, M Saltini, A Hibbel… - researchgate.net
Eukaryotic cells build microtubule arrays with specific and diverse architectures to perform
essential cellular functions, including division and morphogenesis. Central to building and …

Characterization of Saccharomyces cerevisiae kinesin Kip2 by total internal reflection fluorescence microscopy

A Hibbel - 2015 - tud.qucosa.de
(EN) Microtubule length control is indispensable for cytoskeletal functions such as mitotic
spindle assembly and positioning. In vivo studies have shown that kinesin motor proteins can …

[CITATION][C] P2-222 A comparison of whole-brain activation during face encoding between healthy aging, mild cognitive impairment and Alzheimer's disease

SA Rombouts, R Goekoop, A Hibbel, F Barkhof… - Neurobiology of …, 2004 - infona.pl
P2-222 A comparison of whole-brain activation during face encoding between healthy
aging, mild cognitive impairment and Alzheimer's disease