[HTML][HTML] HIGH-MOLECULAR-WEIGHT HYALURONAN—A POTENTIAL ADJUVANT TO FLUID RESUSCITATION IN ABDOMINAL SEPSIS?
AB Tenhunen, J Van Der Heijden, S Dogné, B Flamion… - Shock, 2023 - journals.lww.com
While fluid resuscitation is fundamental in the treatment of sepsis-induced tissue hypoperfusion,
a sustained positive fluid balance is associated with excess mortality. Hyaluronan, an …
a sustained positive fluid balance is associated with excess mortality. Hyaluronan, an …
[HTML][HTML] The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis
A Barrueta Tenhunen, J van der Heijden, I Blokhin… - Plos one, 2020 - journals.plos.org
Sepsis is a life-threatening condition due to a dysregulated immunological response to
infection. Apart from source control and broad-spectrum antibiotics, management is based on …
infection. Apart from source control and broad-spectrum antibiotics, management is based on …
Does the antisecretory peptide AF-16 reduce lung oedema in experimental ARDS?
A Barrueta Tenhunen, F Massaro… - Upsala Journal of …, 2019 - Taylor & Francis
Background: Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition
with pulmonary capillary leakage and lung oedema formation. There is currently no …
with pulmonary capillary leakage and lung oedema formation. There is currently no …
[HTML][HTML] Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis
AB Tenhunen, J van der Heijden, P Skorup… - Intensive care medicine …, 2023 - Springer
Sepsis is a condition with high morbidity and mortality. Prompt recognition and initiation of
treatment is essential. Despite forming an integral part of sepsis management, fluid …
treatment is essential. Despite forming an integral part of sepsis management, fluid …
[HTML][HTML] Adjuvant therapies to fluid resuscitation in experimental sepsis: Intervention studies in models of ARDS and peritonitis
A Barrueta Tenhunen - 2023 - diva-portal.org
In Study IV, we administered an increased dose of HMW-HA directly after induction of peritonitis.
The aim of Study IV was to study the effects of the intervention in a fluid restrictive model…
The aim of Study IV was to study the effects of the intervention in a fluid restrictive model…
High molecular weight hyaluronan–a potential adjuvant to fluid resuscitation in porcine abdominal sepsis
AB Tenhunen, J van der Heijden, W Weigl, R Frithiof… - bioRxiv, 2021 - biorxiv.org
While fluid resuscitation is fundamental in the treatment of sepsis-induced tissue hypo-perfusion,
a sustained positive fluid balance is associated with excess mortality. Crystalloids are …
a sustained positive fluid balance is associated with excess mortality. Crystalloids are …
Does the Antisecretory Peptide AF-16 modulate fluid balance and inflammation in experimental peritonitis induced sepsis?
A Barrueta Tenhunen, J van der Heijden, I Blokhin… - bioRxiv, 2020 - biorxiv.org
Sepsis is a life-threatening condition due to a dysregulated immunological response to
infection. Apart from source control and broad-spectrum antibiotics, management is based on …
infection. Apart from source control and broad-spectrum antibiotics, management is based on …
Does the antisecretory peptide AF-16 reduce lung oedema in experimental ARDS?
F Massaro, HA Hansson, R Feinstein… - Upsala Journal of …, 2019 - europepmc.org
Background: Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition
with pulmonary capillary leakage and lung oedema formation. There is currently no …
with pulmonary capillary leakage and lung oedema formation. There is currently no …