[HTML][HTML] Insights into development and progression of idiopathic pulmonary fibrosis from single cell RNA studies
J Nemeth, A Schundner, M Frick - Frontiers in medicine, 2020 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited
therapeutic options. The current model suggests that chronic or repetitive “micro-injuries” of the …
therapeutic options. The current model suggests that chronic or repetitive “micro-injuries” of the …
SARS-CoV-2 variants of concern hijack IFITM2 for efficient replication in human lung cells
It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human lung cells, …
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human lung cells, …
Electrochemical detection of ATP release in-vitro and in-vivo
ATP is one of the most widely distributed extracellular signaling molecules, regulating many
physiological and pathological processes via activation of purinergic receptors. Extracellular …
physiological and pathological processes via activation of purinergic receptors. Extracellular …
Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA. 1
R Nchioua, A Schundner, S Klute… - Life science …, 2023 - life-science-alliance.org
The IFN system constitutes a powerful antiviral defense machinery. Consequently, effective
IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 in …
IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 in …
[HTML][HTML] A novel fibroblast reporter cell line for in vitro studies of pulmonary fibrosis
J Nemeth, A Schundner, K Quast… - Frontiers in …, 2020 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fatal disease of the lower respiratory tract with restricted
therapeutic options. Repetitive injury of the bronchoalveolar epithelium leads to activation …
therapeutic options. Repetitive injury of the bronchoalveolar epithelium leads to activation …
The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells
Interferons are a major part of the anti-viral innate defense system. Successful pathogens,
including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), need to …
including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), need to …
[HTML][HTML] In Vitro Measurements of Cellular Forces and their Importance in the Lung—From the Sub- to the Multicellular Scale
P Kolb, A Schundner, M Frick, KE Gottschalk - Life, 2021 - mdpi.com
Throughout life, the body is subjected to various mechanical forces on the organ, tissue, and
cellular level. Mechanical stimuli are essential for organ development and function. One …
cellular level. Mechanical stimuli are essential for organ development and function. One …
SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells
It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human cells. To date, …
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human cells. To date, …
The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells (preprint)
Interferons are a major part of the anti-viral innate defense system. Successful pathogens,
including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), need to …
including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), need to …
SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells (preprint)
ABSTRACT It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020)
hijacks interferon-induced transmembrane proteins (IFITMs) for efficient replication in human …
hijacks interferon-induced transmembrane proteins (IFITMs) for efficient replication in human …