Persistent infection or chronic inflammation contributes significantly to tumourigenesis and
tumour progression. CXC motif ligand 8 (CXCL8) is a chemokine that acts as an important …

Immune checkpoint inhibitor (ICI) activates host’s anti-tumor immune response by blocking
negative regulatory immune signals. A series of clinical trials showed that ICI could effectively …

The chimeric antigen receptor T (CAR-T) cell therapy is a newly developed adoptive antitumor
treatment. Theoretically, CAR-T cells can specifically localize and eliminate tumor cells by …

MicroRNAs (miRNAs) are single-stranded, noncoding RNAs that are important in many
biological processes 1 , 2 . Although the oncogenic and tumour-suppressive functions of several …

Antioxidant and antibacterial activities were evaluated by the extracts of Ficus microcarpa,
which is one of the traditional medicinal plant and food additives in Okinawa, Japan. Results …

Angiogenesis has always been the topic of major scientific interest in the field of malignant
tumors. Nowadays, targeting angiogenesis has achieved success in various carcinomas by …

During tumor progression, a subset of cancer cells escape from immune surveillance and
eventually develop into measurable tumor mass. Cancer immunotherapy eradicates tumor …

Background Acute myeloid leukemia (AML) is a common leukemia subtype and has a poor
prognosis. The risk of AML is highly related to age. In the context of population aging, a …

During malignant transformation, accumulated somatic mutations endow cancer cells with
increased invasiveness and immunogenicity. Under selective pressure, these highly …

PTENP1 is a pseudogene of the PTEN tumor suppression gene (TSG). The functions of
PTENP1 in clear-cell renal cell carcinoma (ccRCC) have not yet been studied. We found that …