Osteoarthritis (OA) is associated with chronic debilitating joint pain. Pain is the result of an
emotional and sensory experience and preclinical models of OA can thus be useful to better …

Neuropathic pain is a complex disorder associated with emotional and cognitive deficits that
may impair nociceptive manifestations. There is high inter-individual variability in the …

Simple Summary The mechanisms that underlie pain resulting from metastatic bone disease
remain elusive. This translates to a clinical and socioeconomic burden—targeted therapy is …

Norton, John Ring, Charles EH Rogers, Ebenezer Snell, William Foster Vise, Albert Waymouth,
and W. John Wey. MEDICO-CHIRURGICAL SOCIETY, ABERDEEN. — At a meeting of …

1 We describe here the effects of intrathecal selective adenosine receptor agonists on acute
and more persistent evoked responses of dorsal horn nociceptive neurones recorded in …

: To determine the relationship between potency and lipophilicity for intrathecal opioids,
morphine, normorphine, pethidine and methadone were studied in an electrophysiological …

… by innocuous inputs and not receiving C-fibre inputs are not activated by formalin implying
a role of C fibres in the responses of the convergent neurones to formalin (Dickenson and …

… Department of Psychiatry Sleep Disorders and Research Center Henry Ford Hospital Wayne
State University … 549 Anthony Henry Dickenson, Victoria Chapman, and Alison Reeve …

… DICKENSON focuses primarily on modulatory processes in the central nervous system,
particularly opioids, their diverse central actions, and plasticity in those systems. He also …

: Previous studies have shown that morphine-3-glucuronide (M3G), a metabolite of morphine,
may functionally antagonize the antinociceptive action of morphine. The interaction …