Paclitaxel induces peripheral neuropathy as a side effect of cancer treatment. The underlying
causes are unclear, but epidermal, unmyelinated axons have been shown to be the first to …

Proliferating cell nuclear antigen (PCNA) is a central factor in DNA replication and repair
pathways that plays an essential role in genome stability. The functional roles of PCNA are …

Non-mammalian models of CIPN remain relatively sparse, but the knowledge gained from
the few published studies suggest that these species have great potential to serve as a …

Taxanes are chemotherapeutic agents that induce microtubule modifications in cancer cells,
resulting in cell cycle modifications and tumor remission. Here we show that paclitaxel, a …

Paclitaxel-induced peripheral neuropathy is a condition of nerve degeneration induced by
chemotherapy, which afflicts up to 70% of treated patients. Therapeutic interventions are …

Peripheral neuropathy is a condition of axon degeneration in the hands and feet, which affects
an estimated 30-40 million Americans, leading to pain, numbness, tingling, temperature …

This issue of IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS is available on the
World Wide Web. Access will be limited to members of the IEEE Industry Applications Society …

INTRODUCTION: Multiple myeloma (MM) is preceded by an asymptomatic expansion of
clonal plasma cells leading to precursor conditions labeled as monoclonal gammopathy of …

B cell maturation antigen (BCMA) target loss is considered to be a rare event that mediates
multiple myeloma (MM) resistance to anti-BCMA chimeric antigen receptor T cell (CAR T) or …

INTRODUCTION: Multiple myeloma (MM) evolution is complex and heterogeneous. Hyperdiploidy
(HRD) and translocations affecting the immunoglobulin heavy chain (IGH) locus are …