Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

H Kwon, AN Imbalzano, PA Khavari, RE Kingston… - Nature, 1994 - nature.com
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by
blocking access of sequence-specific activator proteins (activators) to their promoter-binding …

Facilitated binding of TATA-binding protein to nucleosomal DNA

AN Imbalzano, H Kwon, MR Green, RE Kingston - Nature, 1994 - nature.com
BINDING of the TATA-binding protein (TBP) to the TATA box is required for transcription from
many eukaryotic promoters in gene expression. Regulation of this binding is therefore likely …

The Chd family of chromatin remodelers

CGA Marfella, AN Imbalzano - Mutation Research/Fundamental and …, 2007 - Elsevier
Chromatin remodeling enzymes contribute to the dynamic changes that occur in chromatin
structure during cellular processes such as transcription, recombination, repair, and …

Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response

…, SL Gore, R Sridharan, AN Imbalzano… - Genes & …, 2006 - genesdev.cshlp.org
Studies of mammalian genes activated in response to an acute stimulus have suggested
diverse mechanisms through which chromatin structure and nucleosome remodeling events …

Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers

IL De la Serna, Y Ohkawa, AN Imbalzano - Nature Reviews Genetics, 2006 - nature.com
The initiation of cellular differentiation involves alterations in gene expression that depend
on chromatin changes, at the level of both higher-order structures and individual genes. …

p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci

C Simone, SV Forcales, DA Hill, AN Imbalzano… - Nature …, 2004 - nature.com
During skeletal myogenesis, genomic reprogramming toward terminal differentiation is
achieved by recruiting chromatin-modifying enzymes to muscle-specific loci 1 , 2 . The relative …

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation

IL de la Serna, KA Carlson, AN Imbalzano - Nature genetics, 2001 - nature.com
Mammalian SWI/SNF complexes are ATP-dependent chromatin remodeling enzymes that
have been implicated in the regulation of gene expression, cell-cycle control and oncogenesis …

Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

…, W Webster, TW Smith, AN Imbalzano… - … and cellular biology, 2001 - Taylor & Francis
SNF5/INI1 is a component of the ATP-dependent chromatin remodeling enzyme family SWI/SNF.
Germ line mutations ofINI1 have been identified in children with brain and renal …

MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex

…, CS Dacwag, SJ Tapscott, AN Imbalzano - … and cellular biology, 2005 - Taylor & Francis
The activation of muscle-specific gene expression requires the coordinated action of muscle
regulatory proteins and chromatin-remodeling enzymes. Microarray analysis performed in …

Mammalian SWI/SNF complexes facilitate DNA double‐strand break repair by promoting γ‐H2AX induction

…, EJ Park, HS Lee, SJ Kim, SK Hur, AN Imbalzano… - The EMBO …, 2006 - embopress.org
Although mammalian SWI/SNF chromatin remodeling complexes have been well established
to play important role in transcription, their role in DNA repair has remained largely …