User profiles for Anthony W. Wohns

Anthony Wilder Wohns

Stanford University School of Medicine
Verified email at stanford.edu
Cited by 580

Efficient ancestry and mutation simulation with msprime 1.0

…, K Thornton, H Van Kemenade, AW Wohns… - Genetics, 2022 - academic.oup.com
Stochastic simulation is a key tool in population genetics, since the models involved are
often analytically intractable and simulation is usually the only way of obtaining ground-truth …

Inferring whole-genome histories in large population datasets

J Kelleher, Y Wong, AW Wohns, C Fadil, PK Albers… - Nature …, 2019 - nature.com
Inferring the full genealogical history of a set of DNA sequences is a core problem in
evolutionary biology, because this history encodes information about the events and forces that …

Genetic history of Cambridgeshire before and after the Black Death

…, SA Inskip, C Cessford, SA Biagini, AW Wohns… - Science …, 2024 - science.org
The extent of the devastation of the Black Death pandemic (1346–1353) on European
populations is known from documentary sources and its bacterial source illuminated by studies of …

Medieval social landscape through the genetic history of Cambridgeshire before and after the Black Death

…, SA Inskip, C Cessford, SA Biagini, AW Wohns… - BioRxiv, 2023 - biorxiv.org
The extent of the devastation of the Black Death pandemic (1346-53) on European populations
is known from documentary sources and its bacterial source illuminated by studies of …

[HTML][HTML] A general and efficient representation of ancestral recombination graphs

Y Wong, A Ignatieva, J Koskela, G Gorjanc, AW Wohns… - bioRxiv, 2023 - ncbi.nlm.nih.gov
As a result of recombination, adjacent nucleotides can have different paths of genetic
inheritance and therefore the genealogical trees for a sample of DNA sequences vary along the …

Inferring the ancestry of everyone

J Kelleher, Y Wong, PK Albers, AW Wohns, G McVean - BioRxiv, 2018 - biorxiv.org
A central problem in evolutionary biology is to infer the full genealogical history of a set of
DNA sequences. This history contains rich information about the forces that have influenced a …

[CITATION][C] Publisher Correction: Inferring whole-genome histories in large population datasets

J Kelleher, Y Wong, AW Wohns, C Fadil, PK Albers… - Nature Genetics, 2019 - nature.com
In the version of this article initially published, in Table 1, the final three numbers in the ‘Trees’
column were listed as ‘× 106’but should have been ‘× 103’. In addition, the …

A unified genealogy of modern and ancient genomes

AW Wohns, Y Wong, B Jeffery, A Akbari, S Mallick… - Science, 2022 - science.org
The sequencing of modern and ancient genomes from around the world has revolutionized
our understanding of human history and evolution. However, the problem of how best to …

Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

P Salehi Nowbandegani, AW Wohns, JL Ballard… - Nature Genetics, 2023 - nature.com
Linkage disequilibrium (LD) is the correlation among nearby genetic variants. In genetic
association studies, LD is often modeled using large correlation matrices, but this approach is …

Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations

…, P Unneberg, JM Vazquez, RK Waples, AW Wohns… - Elife, 2023 - elifesciences.org
Simulation is a key tool in population genetics for both methods development and empirical
research, but producing simulations that recapitulate the main features of genomic datasets …